Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of the exo-xis region in the regulation of phage development with regard to phage lambda nad Shiga toxin-convering phages responsible for virulence of Escherichia coli enterohemorrhagic strains.

2013/09/B/NZ2/02366

Keywords:

exo-xis region lambdoid phages Shiga toxins EHEC STEC

Descriptors:

  • NZ2_1: Molecular genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Alicja Węgrzyn 

Number of co-investigators in the project: 4

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 926 690 PLN

Project start date (Y-m-d): 2014-02-13

Project end date (Y-m-d): 2017-02-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Wytrząsarka inkubatorowa (6 393 PLN)
  2. Inkubator laboratoryjny (16 000 PLN)
  3. Spektrofotometr z kuwetą na objętości mikrolitrowe (37 000 PLN)
  4. Wirówka z chłodzeniem, rotorami i akcesoriami (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. Different expression patterns of genes from the exo-xis region of bacteriophage lambda and Shiga toxin-converting bacteriophage Phi24B following infection or prophage induction in Escherichia coli
    Authors:
    Sylwia Bloch, Bożena Nejman-Faleńczyk, Aleksandra Dydecka, Joanna M. Łoś, Agnieszka Felczykowska, Alicja Węgrzyn, Grzegorz Węgrzyn
    Academic press:
    PLOS ONE (rok: 2014, tom: 9, strony: e108233), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0108233 - link to the publication
  2. Small regulatory RNAs in lambdoid bacteriophages and phage-derived plasmids: not only antisense
    Authors:
    Bożena Nejman-Faleńczyk, Sylwia Bloch, Katarzyna Licznerska, Agnieszka Felczykowska, Aleksandra Dydecka, Alicja Węgrzyn, Grzegorz Węgrzyn
    Academic press:
    Plasmid (rok: 2015, tom: in press, strony: in press), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.plasmid.2014.07.006 - link to the publication
  3. Bad phages in good bacteria: Role of the mysterious orf63 of lambda and Shiga Toxin-Converting Phi24B bacteriophages
    Authors:
    Dydecka A, Bloch S, Rizvi A, Perez S, Nejman-Falenczyk B, Topka G, Gasior T, Necel A, Wegrzyn G, Donaldson LW, Wegrzyn A
    Academic press:
    Frontiers in Microbiology (rok: 2017, tom: 8, strony: 1618), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmicb.2017.01618 - link to the publication
  4. The Role of the Exo-Xis Region in Oxidative Stress-Mediated Induction of Shiga Toxin-Converting Prophages
    Authors:
    Katarzyna Licznerska, Aleksandra Dydecka,Sylwia Bloch, Gracja Topka, Bożena Nejman-Faleńczyk, Alicja Węgrzyn, Grzegorz Węgrzyn
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2016, tom: 2016, strony: 8453135), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2016/8453135 - link to the publication
  5. Oxidative Stress in Shiga Toxin Production by Enterohemorrhagic Escherichia coli
    Authors:
    Katarzyna Licznerska,Bożena Nejman-Faleńczyk,Sylwia Bloch,Aleksandra Dydecka,Gracja Topka,Tomasz Gąsior, Alicja Węgrzyn, Grzegorz Węgrzyn
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2016, tom: 2016, strony: 3578368), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2016/3578368 - link to the publication
  6. UV-Sensitivity of Shiga Toxin-Converting Bacteriophage Virions Φ24B, 933W, P22, P27 and P32
    Authors:
    Sylwia Bloch, Bożena Nejman-Faleńczyk, Gracja Topka, Aleksandra Dydecka, Katarzyna Licznerska, Magdalena Narajczyk, Agnieszka Necel, Alicja Węgrzyn, Grzegorz Węgrzyn
    Academic press:
    Toxins (rok: 2015, tom: 7, strony: 3727-3739), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/toxins7093727 - link to the publication
  7. A small, microRNA-size, ribonucleic acid regulating gene expression and development of Shiga toxin-converting bacteriophage Φ24Β
    Authors:
    Bożena Nejman-Faleńczyk, Sylwia Bloch, Katarzyna Licznerska, Aleksandra Dydecka, Agnieszka Felczykowska, Gracja Topka, Alicja Węgrzyn, Grzegorz Węgrzyn
    Academic press:
    Scientific Reports (rok: 2015, tom: 5, strony: 10080), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/srep10080 - link to the publication