Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Role of stearoyl-CoA desaturase in epigenic regulation of insulin resistance development in skeletal muscle

2013/09/N/NZ3/03540

Keywords:

Scd-1 DNA methylation insulin resistance skeletal muscle

Descriptors:

  • NZ3_7: Signal transduction
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Dziewulska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2014-02-19

Project end date (Y-m-d): 2016-08-18

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. High-Throughput Approaches onto Uncover (Epi)Genomic Architecture of Type 2 Diabetes
    Authors:
    Anna Dziewulska, Aneta M. Dobosz, Agnieszka Dobrzyn
    Academic press:
    Genes (rok: 2018, tom: 9(8), strony: 374), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes9080374 - link to the publication
  2. SCD1 regulates the AMPK/SIRT1 pathway and histone acetylation through changes in adenine nucleotide metabolism in skeletal muscle
    Authors:
    Dziewulska A, Dobosz AM, Dobrzyn A, Smolinska A, Kolczynska K, Ntambi JM, Dobrzyn P.
    Academic press:
    Journal of Cellular Physiology (rok: 2019, tom: 45469, strony: 45303), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jcp.29026 - link to the publication
  1. Stearoyl-CoA desaturase regulates sirtuin 1 activity in skeletal muscle
    Authors:
    Anna Dziewulska, Pawel Dobrzyn, Aleksandra Pyrkowska, James M. Ntambi, Agnieszka Dobrzyn
    Conference:
    The FEBS EMBO 2014 Conference (rok: 2014, ), Wydawca: FEBS EMBO
    Data:
    konferencja 30.08-04.09
    Status:
    Published
  2. Induced pluripotent stem cells as a model for diabetes investigation
    Authors:
    Anna Dziewulska, Agnieszka Dobrzyn
    Conference:
    EMBO Workshop on Stem Cell Mechanobiology in Development and Disease (rok: 2015, ), Wydawca: EMBO
    Data:
    konferencja 18-21.10
    Status:
    Published
  3. Muscle-specific overexpression of Scd1 affects energy homeostasis and lipid/glucose metabolism in skeletal muscle
    Authors:
    Anna Dziewulska, James M. Ntambi, Agnieszka Dobrzyn
    Conference:
    44th European Muscle Conference (rok: 2015, ), Wydawca: J Muscle Res Cell Motil (2015) 36:535–605 - Springer
    Data:
    konferencja 21-25.09
    Status:
    Published