Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Investigation of amyloid formation process of selected proteins with use of microfluidics

2013/09/N/ST5/02444

Keywords:

amyloidogenesis microfluidics

Descriptors:

  • ST5_16:
  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST5_9: Biomaterials, biocompatible materials

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Witold Gospodarczyk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 124 450 PLN

Project start date (Y-m-d): 2014-03-04

Project end date (Y-m-d): 2017-07-03

Project duration:: 40 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. układy mikrofluidyczne oraz pompy mikrofluidyczne (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (4)
  1. The severe impact of in vivo-like microfluidic flow and the influence of gemini surfactants on amyloid aggregation of hen egg white lysozyme
    Authors:
    W. Gospodarczyk, M. Kozak
    Academic press:
    RSC Advances (rok: 2017, tom: 7, strony: 10973-10984), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c6ra26675d - link to the publication
  2. Microchip Circulation Drastically Accelerates Amyloid Aggregation of 1-42 β-amyloid Peptide from Felis catus
    Authors:
    W. Gospodarczyk, M. Kozak
    Academic press:
    ACS Chemical Neuroscience (rok: 2017, tom: 8 (11), strony: 2558–2567), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acschemneuro.7b00285 - link to the publication
  1. Influence of microfluidic flow on amyloid aggregation of hen egg white lysozyme
    Authors:
    W. Gospodarczyk, M. Kozak
    Conference:
    11. Krajowe Sympozjum Użytkowników Promieniowania Synchrotronowego (rok: 2015, ), Wydawca: Synchrotron Radiation in Natural Science
    Data:
    konferencja 1-4 września
    Status:
    Published
  2. Design of microfluidic device for the spectroscopic and structural studies of protein amyloidogenesis
    Authors:
    W. Gospodarczyk, M. Kozak
    Conference:
    International Meeting CYSTATINS 2014 (rok: 2014, ), Wydawca: Wydział Chemii Uniwersytetu Gdańskiego
    Data:
    konferencja 12-14 czerwca
    Status:
    Published
  3. A role of microfluidic flow and gemini surfactants in amyloid aggregation of lysozyme and other proteins
    Authors:
    W. Gospodarczyk, M. Kozak
    Conference:
    13th International School and Symposium on Synchrotron Radiation in Natural Science (rok: 2016, ), Wydawca: Synchrotron Radiation in Natural Science
    Data:
    konferencja 13-18 czerwca
    Status:
    Published
  4. Amyloidogenesis of human cystatin C and other proteins induced by microflow
    Authors:
    W. Gospodarczyk, M. Kozak
    Conference:
    International Meeting Cystatins 2016 (rok: 2016, ), Wydawca: Lunds Universitet
    Data:
    konferencja 2-4 czerwca
    Status:
    Published