Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of human secretome and circulating microRNA in the diagnosis of early, asymptomatic phase of age-related macular degeneration (AMD)- epidemiological implications

2013/09/B/NZ7/04031

Keywords:

Age-related macular degeneration AMD genetic biomarkers proteomic biomarkers epidemiology early diagnosis prevention

Descriptors:

  • NZ7_12: Prevention of human diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

woj. zachodniopomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Anna Machalińska 

Number of co-investigators in the project: 5

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 508 200 PLN

Project start date (Y-m-d): 2014-04-07

Project end date (Y-m-d): 2018-04-06

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Kamera do wizualizacji dna oka.
  2. Moduł do pomiaru saturacji krwi tlenem w naczyniach siatkówki (100 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. The role of microRNA in the pathogenesis of age-related macular degeneration: its pathophysiology and potential pharmacological aspects.
    Authors:
    Miłosz Kawa, Anna Machalińska.
    Academic press:
    J. Biochem. Pharmacol. Res. (rok: 2014, tom: vol. 2, nr 1,, strony: s. 21-32,), Wydawca: Research Publisher
    Status:
    Published
    DOI:
    brak - link to the publication
  2. The Interplay Between Systemic Inflammatory Factors and MicroRNAs in Age-Related Macular Degeneration
    Authors:
    Litwińska Z, Sobuś A, Łuczkowska K, Grabowicz A, Mozolewska-Piotrowska K, Safranow K, Kawa MP, Machaliński B, Machalińska A.
    Academic press:
    Frontiers in Aging Neuroscience (rok: 2019, tom: 11, strony: 286-299), Wydawca: Lausanne : Frontiers Research Foundation
    Status:
    Published
    DOI:
    10.3389/fnagi.2019.00286 - link to the publication
  3. Associations of microRNAs, Angiogenesis-Regulating Factors and CFH Y402H Polymorphism-An Attempt to Search for Systemic Biomarkers in Age-Related Macular Degeneration
    Authors:
    Ulańczyk Z, Sobuś A, Łuczkowska K, Grabowicz A, Mozolewska-Piotrowska K, Safranow K, Kawa MP, Pałucha A, Krawczyk M, Sikora P, Matczyńska E, Machaliński B, Machalińska A
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: 5750), Wydawca: Basel, Switzerland: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20225750 - link to the publication
  1. MicroRNA expressed in progenitor cells circulating in peripheral blood as prospective biomarkers of age-related macular degeneration (AMD) in its dry and wet form – preliminary data
    Authors:
    A. Machalińska, M.P. Kawa, A. Sobuś, Z. Litwińska, A. Kowalska-Budek, K. Babiak, A. Grabowicz, B. Machaliński
    Conference:
    BORDEAUX VIVA WINTER SCHOOL - XXXIII LIAC MEETING (rok: 2017, ), Wydawca: ALIES - Associação Lusófona para o Desenvolvimento
    Data:
    konferencja 29.11-01.12.2017
    Status:
    Published
    DOI:
    link to the publication

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