The role of human secretome and circulating microRNA in the diagnosis of early, asymptomatic phase of age-related macular degeneration (AMD)- epidemiological implications

2013/09/B/NZ7/04031

Keywords

Descriptors

  • NZ7_12: Prewencja chorób człowieka

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Voivodeship: zachodniopomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Anna Machalińska

Number of co-investigators in the project: 5

Call

OPUS 5 – announced on 2013-03-15

Amount awarded
508 200 PLN
Project start date
2014-04-07
Project end date
2018-04-06
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Kamera do wizualizacji dna oka.
  2. Moduł do pomiaru saturacji krwi tlenem w naczyniach siatkówki. Cost: 100 000 PLN

Information in the final report

Publication in academic press/journals (3)

  1. The role of microRNA in the pathogenesis of age-related macular degeneration: its pathophysiology and potential pharmacological aspects.

    Authors:
    Miłosz Kawa, Anna Machalińska.
    Academic press:
    J. Biochem. Pharmacol. Res. (year: 2014, volume: vol. 2, nr 1,, pages: s. 21-32,), Publisher: Research Publisher
    Status:
    Published
  2. Associations of microRNAs, Angiogenesis-Regulating Factors and CFH Y402H Polymorphism-An Attempt to Search for Systemic Biomarkers in Age-Related Macular Degeneration

    Authors:
    Ulańczyk Z, Sobuś A, Łuczkowska K, Grabowicz A, Mozolewska-Piotrowska K, Safranow K, Kawa MP, Pałucha A, Krawczyk M, Sikora P, Matczyńska E, Machaliński B, Machalińska A
    Academic press:
    International Journal of Molecular Sciences (year: 2019, volume: 20, pages: 5750), Publisher: Basel, Switzerland: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20225750 – link to the publication
  3. The Interplay Between Systemic Inflammatory Factors and MicroRNAs in Age-Related Macular Degeneration

    Authors:
    Litwińska Z, Sobuś A, Łuczkowska K, Grabowicz A, Mozolewska-Piotrowska K, Safranow K, Kawa MP, Machaliński B, Machalińska A.
    Academic press:
    Frontiers in Aging Neuroscience (year: 2019, volume: 11, pages: 286-299), Publisher: Lausanne : Frontiers Research Foundation
    Status:
    Published
    DOI:
    10.3389/fnagi.2019.00286 – link to the publication

Articles in post-conference publications (1)

  1. MicroRNA expressed in progenitor cells circulating in peripheral blood as prospective biomarkers of age-related macular degeneration (AMD) in its dry and wet form – preliminary data

    Authors:
    A. Machalińska, M.P. Kawa, A. Sobuś, Z. Litwińska, A. Kowalska-Budek, K. Babiak, A. Grabowicz, B. Machaliński
    Conference:
    BORDEAUX VIVA WINTER SCHOOL - XXXIII LIAC MEETING (year: 2017, pages: 287-309), Publisher: ALIES - Associação Lusófona para o Desenvolvimento
    Date:
    conference 29.11-01.12.2017
    Status:
    Published
    DOI:
    link to the publication

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Graphic design and implementation: Jakub Piotrowski