Projects funded by the NCN
Identification of proteins influencing degradation of CD20 antigen
2013/09/N/NZ3/01407
Keywords:
CD20 monoclonal antibodies HDAC6 protein degradation
Descriptors:
- NZ2_3: Proteomics
- NZ1_1: Molecular biology
- NZ3_1: Cell biology
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Warszawski Uniwersytet Medyczny, I Wydział Lekarski
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 5 - announced on 2013-03-15
Amount awarded: 99 999 PLN
Project start date (Y-m-d): 2014-03-11
Project end date (Y-m-d): 2016-03-10
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (1)
- HDAC6 inhibition up-regulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodiesAuthors:Malgorzata Bobrowicz M, Michal Dwojak, Beata Pyrzynska , Joanna Stachura, Angelika Muchowicz , Elise Berthel , Nicole Dalla Venezia , Mieszko Kozikowski, Marta Siernicka, Nina Miazek , Piotr Zapala , Antoni Domagala , Kamil Bojarczuk , Agata Malenda , Joanna Barankiewicz, Agnieszka Graczyk-Jarzynka , Agnieszka Zagozdzon , Magdalena Gabrysiak , Jean-Jacques Diaz , Marta Karp , Ewa Lech-Maranda, Malgorzata Firczuk , Krzysztof Giannopoulos, Dimitar G Efremov , Luca Laurenti, Dunja Baatout, Lukas Frenzel, Agata Malinowska, Mikolaj Slabicki, Thorsten Zenz, Abdessamad Zerrouqi , Jakub Golab, Magdalena WiniarskaAcademic press:Blood (rok: 2017, tom: 130, strony: 1628-1638), Wydawca: Nature Publishing GroupStatus:PublishedDOI:10.1182/blood-2016-08-736066 - link to the publication