IDENTIFICATION AND STRUCTURAL STUDIES OF NEW PSYCHOACTIVE SUBSTANCES IN SYNTHETIC NARCOTICS OF LAST GENERATION USING ORGANIC CHEMICAL METHODS LC-MS, GC-MS AND NMR

2013/09/B/ST4/00106

Keywords

Descriptors

  • ST4_6: Chemia analityczna
  • ST4_3: Metody spektroskopowe i spektrometryczne
  • NZ7_4: Prewencja populacyjna

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Narodowy Instytut Leków

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Lech Jan Kozerski

Number of co-investigators in the project: 11

Call

OPUS 5 – announced on 2013-03-15

Amount awarded
905 040 PLN
Project start date
2014-10-01
Project end date
2018-09-30
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Chromatograf gazowy do MS. Cost: 70 000 PLN
  2. Chłodziarko-zamrażarka laboratoryjna. Cost: 12 000 PLN
  3. Komputer (do obróbki danych graficznych). Cost: 10 000 PLN
  4. Liofilizator laboratoryjny. Cost: 35 000 PLN
  5. Osuszacz powietrza do układu sprężonego powietrza. Cost: 10 000 PLN
  6. Preparatywny HPLC. Cost: 4 485 PLN

Information in the final report

Publication in academic press/journals (3)

  1. Identification and structural characterization of synthetic cathinones: N‑propylcathinone, 2,4‑dimethylmethcathinone, 2,4‑dimethylethcathinone, 2,4‑dimethyl‑α‑pyrrolidino propiophenone, 4‑bromo‑α‑pyrrolidinopropiophenone, 1‑(2,3‑dihydro‑1H‑inden‑5‑yl)‑2‑(pyrrolidin‑1‑yl)hexan‑1‑one and 2,4‑dimethylisocathinone

    Authors:
    Agata Błażewicz, Elżbieta Bednarek, Magdalena Popławska, Natalia Olech, Jerzy Sitkowski, Lech Kozerski
    Academic press:
    Forensic Toxicology (year: 2019, volume: 37, pages: 288-307), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s11419-018-00463-w – link to the publication
  2. Application of high-performance liquid chromatography with charged aerosol detection (LC-CAD) for unified quantification of synthetic cannabinoids in herbal blends and comparison with quantitative NMR results

    Authors:
    M. Poplawska, A. Błażewicz, K. Kamiński, E. Bednarek, Z. Fijałek, L. Kozerski
    Academic press:
    Forensic Toxicology (year: 2018, volume: 36, pages: 122-140), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s11419-017-0392-7 – link to the publication
  3. Identification and structural characterization of four novel synthetic cathinones: alfa-methylaminohexanophenone(hexedrone, HEX), 4-bromoethcathinone(4-BEC), 4-chloro-alfa-pyrrolidynopropiophenone (4Cl-PPP), and 4-bromo-alfa-pyrrolidynopentiophenone (4-Br-PVP) after their seizures

    Authors:
    A. Błażewicz, E. Bednarek, J. Sitkowski, M. Popławska, K. Stypułkowska, W.Bocian, L. Kozerski
    Academic press:
    Forensic Toxicology (year: 2017, volume: 35, pages: 317-332), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s11419-017-0360-2 – link to the publication

Book publications / chapters in book publications (1)

  1. Nowe substancje psychoaktywne - Substancje aktywne farmakologicznie wykryte w tzw. dopalaczach - środkach zastępczych

    Authors:
    Z. Fijałek, A. Błażewicz, M. Popławska, E. Bednarek, J. Sitkowski, W. Bocian, M. Kiljan, K. Stypułkowska, Z. Chilmonczyk, G. Karpińska, L. Kozerski
    Book:
    Nowe substancje psychoaktywne - Substancje aktywne farmakologicznie wykryte w tzw. dopalaczach - środkach zastępczych (year: 2015, volume: -, pages: 1-180), Publisher: NIL
    Status:
    Published
    DOI:
    link to the publication

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Graphic design and implementation: Jakub Piotrowski