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Information on the principal investigator and host institution

Information of the project and the call

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The impact of endotoxemia on ischemic stroke outcome.

2013/09/B/NZ4/01572

Keywords:

stroke outcome endotoxin inflammation

Descriptors:

  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Tomasz Dziedzic 

Number of co-investigators in the project: 5

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 702 613 PLN

Project start date (Y-m-d): 2014-03-04

Project end date (Y-m-d): 2017-03-03

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. Reduced release of TNFα and IP-10 after ex vivo blood stimulation with endotoxin is associated with poor outcome after stroke.
    Authors:
    Klimiec E, Kowalska K, Pasinska P, Pera J, Slowik A, Dziedzic T.
    Academic press:
    Cytokine (rok: 2018, tom: 102, strony: 51-54), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cyto.2017.12.015. - link to the publication
  2. Plasma endotoxin activity rises during ischemic stroke and is associated with worse short-term outcome.
    Authors:
    Klimiec E, Pera J, Chrzanowska-Wasko J, Golenia A, Slowik A, Dziedzic T.
    Academic press:
    J Neuroimmunol. (rok: 2016, tom: 297, strony: 76-80), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jneuroim.2016.05.006. - link to the publication
  3. The association between plasma endotoxin, endotoxin pathway proteins and outcome after ischemic stroke.
    Authors:
    Klimiec E, Pasinska P, Kowalska K, Pera J, Slowik A, Dziedzic T.
    Academic press:
    Atherosclerosis (rok: 2018, tom: 269, strony: 138-143), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.atherosclerosis.2017.12.034. - link to the publication
  4. Systemic inflammation as a therapeutic target in acute ischemic stroke.
    Authors:
    Dziedzic T.
    Academic press:
    Expert Rev Neurother. (rok: 2015, tom: 15, strony: 523-531), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1586/14737175.2015.1035712 - link to the publication