The transferrin and transferrin receptor, role in ruthenium complexes transport into the cytosol of cancer cells

2013/09/N/ST5/00858

Keywords

Descriptors

  • ST5_16: Chemia biologiczna
  • ST5_20: Chemia pojedynczych cząsteczek i makrocząsteczek
  • ST5_14: Chemia koordynacyjna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Uniwersytet Jagielloński, Wydział Chemii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Klaudyna Joanna Śpiewak

Number of co-investigators in the project: 2

Call

PRELUDIUM 5 – announced on 2013-03-15

Amount awarded
149 994 PLN
Project start date
2014-03-25
Project end date
2017-03-24
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Automatyczny licznik komórek. Cost: 13 000 PLN
  2. Pipety automatyczne. Cost: 2 500 PLN
  3. Urządzenie do produkcji lody kruszonego. Cost: 4 000 PLN
  4. Wytrząsarki (Vortex). Cost: 1 508 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Impact of low- and high-molecular-mass components of human serum on NAMI-A binding to transferrin

    Authors:
    K. Śpiewak, M. Brindell
    Academic press:
    J. Biol. Inorg. Chem. (year: 2015, volume: 20, pages: 695-703), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00775-015-1255-5 – link to the publication
  2. Influence of redox activation of NAMI-A on affinity to serum proteins: transferrin and albumin

    Authors:
    K. Śpiewak, G. Stochel, M. Brindell
    Academic press:
    J. Coord. Chem. (year: 2015, volume: 68, pages: 3181-3192), Publisher: Taylor & Francis Group
    Status:
    Published
    DOI:
    10.1080/00958972.2015.1067692 – link to the publication

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Graphic design and implementation: Jakub Piotrowski