Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Epigenetic basis of increased susceptibility of infections with Herpes viruses - analysis of microRNA role in patien tssuspected of having a primary immunodeficiency disease

2013/09/D/NZ2/01660

Keywords:

microRNA viral infections Herpesviridae primary immunodeficiencies

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_1: Molecular genetics
  • NZ6_2: Clinical immunology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marzena Lenart 

Number of co-investigators in the project: 5

Call: SONATA 5 - announced on 2013-03-15

Amount awarded: 523 692 PLN

Project start date (Y-m-d): 2014-02-20

Project end date (Y-m-d): 2020-07-19

Project duration:: 77 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. Selective downregulation of natural killer activating receptors on NK cells and upregulation of PD-1 expression on T cells in children with severe and/or recurrent Herpes simplex virus infections
    Authors:
    Marzena Lenart, Anna Kluczewska, Anna Szaflarska, Magdalena Rutkowska-Zapała, Magdalena Wąsik, Anna Ziemiańska-Pięta, Krzysztof Kobylarz, Anna Pituch-Noworolska, Maciej Siedlar
    Academic press:
    Immunobiology (rok: 2021, tom: 226(3):152097, strony: 152097), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.imbio.2021.152097 - link to the publication
  2. miRNA Regulation of NK Cells Antiviral Response in Children With Severe and/or Recurrent Herpes Simplex Virus Infections
    Authors:
    Marzena Lenart, Edyta Działo, Anna Kluczewska, Kazimierz Węglarczyk, Anna Szaflarska, Magdalena Rutkowska-Zapała, Marcin Surmiak, Marek Sanak, Anna Pituch-Noworolska, Maciej Siedlar
    Academic press:
    Frontiers in Immunology (rok: 2021, tom: 11:589866, strony: 589866), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2020.589866 - link to the publication

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