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Information on the principal investigator and host institution

Information of the project and the call

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Activity of peripheral blood mononuclear cells in patients with axial and peripheral spondyloarthritis - pathogenetic implications.

2013/09/B/NZ6/02545

Keywords:

human monocytes spondyloarthritis bone remodeling proteins miRNA extracellular microvesicles

Descriptors:

  • NZ6_2: Clinical immunology
  • NZ6_8: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Maciej Siedlar 

Number of co-investigators in the project: 10

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 1 465 477 PLN

Project start date (Y-m-d): 2014-04-01

Project end date (Y-m-d): 2019-03-31

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  1. Down-Regulation of Dkk-1 in Platelets of Patients With Axial Spondyloarthritis.
    Authors:
    Czepiel M, Stec M, Korkosz M, Guła Z, Błyszczuk P, Baran J, Siedlar M.
    Academic press:
    Arthritis Rheumatol. (rok: 2021, tom: 73 (10), strony: 1831-1834), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/art.41739 - link to the publication
  2. Results from Polish Spondyloarthritis Initiative registry (PolSPI) - methodology and data from - the first year of observation.
    Authors:
    Guła Z, Barczyńska T, Brzosko M, Gąsowski J, Jeka S, Jodłowska-Cicio K, Kwaśny-Krochin B, Leszczyński P, Lubiński Ł, Łosińska K, Pawlak-Buś K, Przepiera-Będzak H, Samborski W, Schlabs M, Siedlar M, Sikorska D, Świerkot J, Węgierska M, Wiland P, Korkosz M.
    Academic press:
    Reumatologia/Rheumatology (rok: 2017, tom: 55(2), strony: 59-64), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/reum.2017.67599 - link to the publication
  3. Expression of VEGFA-mRNA in classical and MSX2-mRNA in non-classical monocytes in patients with spondyloarthritis is associated with peripheral arthritis.
    Authors:
    Stec M, Seweryn M, Korkosz M, Guła Z, Szatanek R, Węglarczyk K, Rutkowska-Zapała M, Lenart M, Czepiel M, Czyż J, Baran J, Gruca A, Wojnar-Lasoń K, Wołkow P, Siedlar M.
    Academic press:
    Sci Rep. (rok: 2021, tom: 11(1), strony: 9693-9699), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-021-89037-2 - link to the publication
  4. The absolute number of circulating nonclassical (CD14+CD16++) monocytes negatively correlates with DAS28 and swollen joint count in patients with peripheral spondyloarthritis.
    Authors:
    Guła Z, Stec M, Rutkowska-Zapała M, Lenart M, Korkosz M, Gąsowski J, Baran J, Baj-Krzyworzeka M, Szatanek R, Czyż J, Siedlar M.
    Academic press:
    Pol Arch Intern Med. (rok: 2017, tom: 127(12), strony: 846-853), Wydawca: Published by Medycyna Praktyczna Journal of the Polish Society of Internal Medicine
    Status:
    Published
    DOI:
    10.20452/pamw.4142 - link to the publication
  5. Sera of patients with axial spondyloarthritis (axSpA) enhance osteoclastogenic potential of monocytes isolated from healthy individuals.
    Authors:
    Korkosz M, Czepiel M, Guła Z, Stec M, Węglarczyk K, Rutkowska-Zapała M, Gruca A, Lenart M, Baran J, Gąsowski J, Błyszczuk P, Siedlar M.
    Academic press:
    BMC Musculoskeletal Disorders (rok: 2018, tom: 19, strony: 434-442), Wydawca: BMC Part of Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12891-018-2356-4 - link to the publication

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