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Polyvalent proteinaceus biodegradable vector for intracellular delivery, adenovirus dodecahedron

2013/09/B/NZ3/02327

Keywords

Descriptors

  • NZ3_1: Biologia komórki
  • NZ3_2: Fizjologia komórki

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Instytut Biochemii i Biofizyki PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Ewa Szołajska

Number of co-investigators in the project: 8

Call

OPUS 5 – announced on 2013-03-15

Amount awarded
813 112 PLN
Project start date
2014-02-12
Project end date
2017-02-11
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Komputer z oprogramowaniem. Cost: 5 500 PLN

Information in the final report

Publication in academic press/journals (5)

  1. Review Virus-like particles as drug delivery vectors

    Authors:
    Zdanowicz Michał, Chroboczek Jadwiga
    Academic press:
    Acta Biochimica Polonica (year: 2016, volume: 63, pages: 469-73), Publisher: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/abp.2016_1275 – link to the publication

  2. Virus-like particles as vaccine.

    Authors:
    Chroboczek Jadwiga, Szurgot Inga, Szolajska Ewa
    Academic press:
    Acta Biochimica Polonica (year: 2014, volume: 61, pages: 531-539), Publisher: Polskie Towarzystwo Biochemiczne
    Status:
    Published

  3. Leukocytes and drug-resistant cancer cells are targets for intracellular delivery by adenoviral dodecahedron

    Authors:
    Marta Jedynak, David Laurin, Patryk Dolega, Malgorzata Podsiadla-Bialoskorska, Inga Szurgot, Jadwiga Chroboczek, Ewa Szolajska
    Academic press:
    Nanomedicine: Nanotechnology, Biology, and Medicine (year: 2018, volume: 14, pages: 1853-1865), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.nano.2018.05.001 – link to the publication

  4. Adenovirus dodecahedron, a VLP, can be purified by size exclusion chromatography instead of time-consuming sucrose density gradient centrifugation

    Authors:
    Szurgot Inga, Jedynak Marta, Podsiadla-Białoskorska Małgorzata, Piwowarski Jan, Szołajska Ewa, Chroboczek Jadwiga
    Academic press:
    Molecular Biotechnology (year: 2015, volume: 46079, pages: Epub ahead of print), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s12033-015-9850-9 – link to the publication

  5. Cholesterol and phosphatidylserine are engaged in adenoviral dodecahedron endocytosis

    Authors:
    Marta Jedynak, Remigiusz Worch, Małgorzata Podsiadła-Białoskórska, Jadwiga Chroboczek, Ewa Szołajska
    Status:
    Accepted for publication

Articles in post-conference publications (5)

  1. Adenovirus dodecahedron use as drug and antigen nanoplatform for cancer therapy

    Authors:
    JEDYNAK M., SZURGOT I., PODSIADŁA-BIAŁOSKÓRSKA M., CHROBOCZEK J., SZOŁAJSKA E.
    Conference:
    4th International Conference on Nanotechnology in Medicine, Warsaw, Poland (year: 2016, pages: 85-86), Publisher: Warsaw University of Life Sciences
    Date:
    conference 7-9 listopada
    Status:
    Published

  2. Use of biomolecules delivery vector, adenovirus dodecahedron, for targeted cancer therapy.

    Authors:
    JEDYNAK M., SZURGOT I., ŻOCHOWSKA M., SZOŁAJSKA E., JEMIELITY J., DUFOUR J.F., CHROBOCZEK J.
    Conference:
    40th FEBS Congress: The Biochemical Basis of Life (year: 2015, pages: 395), Publisher: Wiley Online Library
    Date:
    conference 4-9 lipca
    Status:
    Published

  3. Adenovirus dodecahedron as a nanoplatform for cancer therapy.

    Authors:
    SZOŁAJSKA E., JEDYNAK M., LAURIN D., PODSIADŁA-BIAŁOSKÓRSKA M., ŻOCHOWSKA M., CHROBOCZEK J.
    Conference:
    BIT's 7th Annual International Symposium of Drug Delivery Systems, Prague, Czech Republic (year: 2017, pages: Abstract Book p.100), Publisher: BIT Group Global Ltd.
    Date:
    conference 12-14 July
    Status:
    Published

  4. Evaluation of adenoviral dodecahedron in vivo tropism.

    Authors:
    JEDYNAK M., SZURGOT I., ŻOCHOWSKA M., PODSIADŁA-BIAŁOSKÓRSKA M., CHROBOCZEK J., SZOŁAJSKA E.
    Conference:
    ICONAN - International Conference of Nanomedicine and Nanobiotechnology, Barcelona, Spain (year: 2017, pages: Book of Abstracts p.150), Publisher: Pompeu Fabra University, Barcelona
    Date:
    conference 25-27 September
    Status:
    Published

  5. Application of Adenovirus dodecahedron delivery vector as a new approach in overcoming drug resistance.

    Authors:
    JEDYNAK M., DOLEGA P., PODSIADŁA-BIAŁOSKÓRSKA M., CHROBOCZEK J., SZOŁAJSKA E.
    Conference:
    6th Central European Congress of Life Sciences EUROBIOTECH, Kraków, Poland, 11-14 September (year: 2017, pages: Programme and Abstracts Book P15&18.3 p.174), Publisher: Targi w Krakowie
    Date:
    conference 11-14 September
    Status:
    Published
    DOI:
    link to the publication

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