Projects funded by the NCN
The first developmental decisions: cell differentiation in preimplantation mouse embryo
2013/09/B/NZ3/02404
Keywords:
mouse embryo blastocyst differentiation trophectoderm inner cell mass primitive endoderm epiblast
Descriptors:
- NZ3_13: Developmental biology in animals
- NZ3_1: Cell biology
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Uniwersytet Warszawski, Wydział Biologii
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: OPUS 5 - announced on 2013-03-15
Amount awarded: 720 000 PLN
Project start date (Y-m-d): 2014-02-12
Project end date (Y-m-d): 2017-02-11
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Inkubator CO2 do hodowli komórkowych z funkcją dezynfekcji termicznej (autosterylizacja).
- System do poklatkowej rejestracji przebiegu rozwoju zarodków w hodowli (55 000 PLN)
- Mikroskop stereoskopowy klasy badawczej (35 000 PLN)
- Autoklaw (6 000 PLN)
- Mikroskop stereoskopowy 2 sztuki.
- Płytka grzejna do mikroskopu (7 202 PLN)
Information in the final report
- Publication in academic press/journals (3)
- ESCs injected into the 8-cell stage mouse embryo modify pattern of cleavage and cell lineage specificationAuthors:Monika Humięcka, Magdalena Krupa, Maria M. Guzewska, Marek Maleszewski, Aneta SuwińskaAcademic press:Mechanisms of Development (rok: 2016, tom: 141, strony: 40-50), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.mod.2016.06.002 - link to the publication
- Downregulation of E-cadherin does not influence cell fate or spatial separation of Epi and PrE in mouse blastocystAuthors:Katarzyna Filimonow, Nestor Saiz, Aneta Suwińska, Tomasz Wyszomirski, Joanna B. Garbarek, Elizabetta Ferretti, Berenika Płusa, Marek MaleszewskiAcademic press:PLOS One , Wydawca: -Status:SubmittedDOI:brak - link to the publication
- Plasticity of the inner cell mass in mouse blastocyst is restricted by the activity of FGF/MAPK pathwayAuthors:Wigger, M., Świtoń, K., Filimonow, K., Plusa, B., Maleszewski, M., Suwinska, A.Academic press:Scientific Reports (rok: 2017, tom: 7, strony: 15136), Wydawca: Springer NatureStatus:PublishedDOI:10.1038/s41598-017-15427-0 - link to the publication