Projects funded by the NCN
New insight at cadmium carcinogenesis. Cd(II)XPAzf and Zn(II)XPAzf complexes in mild oxydative conditions.
2012/07/N/NZ1/03090
Keywords:
XPAzf GSNO NO carcinogenesis cadmium zinc Cd Zn S-Nitrosothiolaton zf oxidation
Descriptors:
- NZ7_15: Toxicology
- NZ1_2: Biochemistry
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Instytut Biochemii i Biofizyki PAN
woj. mazowieckie
Principal investigator (from the host institution):
Aleksandra Witkiewicz-Kucharczyk
Number of co-investigators in the project: 2
Call: PRELUDIUM 4 - announced on 2012-09-15
Amount awarded: 49 907 PLN
Project start date (Y-m-d): 2013-06-19
Project end date (Y-m-d): 2014-09-18
Project duration:: 15 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (1)
- The Reactions of H2O2 and GSNO with the Zinc Finger Motif of XPA. Not A Regulatory Mechanism, But No Synergy with Cadmium ToxicityAuthors:Aleksandra Witkiewicz-Kucharczyk, Wojciech Goch, Jacek Olędzki, Andrea Hartwig, Wojciech BalAcademic press:Molecules (rok: 2020, tom: 25, strony: 4177-1486), Wydawca: MDPIStatus:PublishedDOI:10.3390/molecules25184177 - link to the publication