Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Theranostic GdLip: Bifunctional liposomes as carriers of gadolinium ions and phthalocyanine photosensitizers for potential application in MR imaging and photodynamic therapy

2012/07/N/NZ7/04325

Keywords:

theranostic liposomes photodynamic therapy phthalocyanines gadolinium MRI

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_16: Other related subjects
  • NZ5_9: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Łukasz Sobotta 

Number of co-investigators in the project: 3

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2013-07-15

Project end date (Y-m-d): 2017-04-14

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (5)
  1. Theranostic liposomes as a bimodal carrier for magnetic resonance imaging contrast agent and photosensitizer
    Authors:
    Paulina Skupin-Mrugalska, Lukasz Sobotta, Alicja Warowicka, Beata Wereszczynska, Tomasz Zalewski, Piotr Gierlich, Marcin Jarek, Grzegorz Nowaczyk, Marek Kempka, Jacek Gapinski, Stefan Jurga, Jadwiga Mielcarek
    Academic press:
    Journal of Inorganic Biochemistry (rok: 2018, tom: 180, strony: 45305), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jinorgbio.2017.11.025 - link to the publication
  2. Cellular changes, molecular pathways and the immune system following photodynamic treatment
    Authors:
    Skupin-Mrugalska P., Sobotta L., Kucińska M., Murias M., Mielcarek J., Düzgüneş N.
    Academic press:
    Current Medicinal Chemistry (rok: 2014, tom: 21, strony: 4059 - 4073), Wydawca: Bentham Science
    Status:
    Published
  1. An overview on nanoplatforms for theranostic application
    Authors:
    Łukasz Sobotta, Wojciech Chudziński, Paulina Skupin-Mrugalska, Jadwiga Mielcarek
    Conference:
    4th Summer Symposium on Nanomaterials and their Application to Biology and Medicine (rok: 2014, ), Wydawca: Uniwersytet im. Adama Mickiewicza w Poznaniu
    Data:
    konferencja 15 - 18 czerwiec 2014
    Status:
    Published
  2. Therenostic GdLip as bimodal carrier for magnetic resonance imaging contrast agent and photosensitizer
    Authors:
    Paulina Skupin-Mrugalska, Lukasz Sobotta, Beata Wereszczynska, Alicja Warowicka, Tomasz Zalewski, Jadwiga Mielcarek, Jacek Gapinski, Stefan Jurga
    Conference:
    Liposome Advances: Progress in Drug and Vaccine Delivery (rok: 2015, ), Wydawca: UCL School of Pharmacy, London
    Data:
    konferencja 19 - 22 grudzień
    Status:
    Published
  3. Bifunctional liposomes for magnetic resonance imaging and photodynamic therapy of cancer
    Authors:
    Paulina Skupin-Mrugalska, Lukasz Sobotta, Beata Wereszczynska, Alicja Warowicka, Tomasz Zalewski, Jadwiga Mielcarek, Jacek Gapinski, Stefan Jurga
    Conference:
    26th Bilateral Symposium Poznan-Halle: From Molecular Medicine to Public Health - Translational Research in Cardiovascular Medicine and Oncology (rok: 2015, ), Wydawca: Martin Luther University Halle-Wittenberg
    Data:
    konferencja 23 - 25 październik
    Status:
    Published
  4. Liposome Bearing Zinc Phthalocyanine and Gadolinium Ions for Magnetic Resonance Imaging and Phodynamic Therapy
    Authors:
    Lukasz Sobotta, Paulina Skupin-Mrugalska, Beata Wereszczynska, Alicja Warowicka, Tomasz Zalewski, Marcin Jarek, Jadwiga Mielcarek, Jacek Gapinski, Stefan Jurga
    Conference:
    the Ninth International conference on Porphyrins and Phthalocyanines (ICPP-9) (rok: 2016, ), Wydawca: Society of Porphyrins & Phthalocyanines, France
    Data:
    konferencja 3 - 8 lipiec
    Status:
    Published
  5. Affinity of phthalocyanine derivatives toward liposome carrier
    Authors:
    Paulina Skupin-Mrugalska, Łukasz Sobotta, Jadwiga Mielcarek
    Conference:
    4th Summer Symposium on Nanomaterials and their Aplication to Biology and Medicine (rok: 2014, ), Wydawca: Uniwersytet im. Adama Mickiewicza w Poznaniu
    Data:
    konferencja 15 - 18 czerwiec 2014
    Status:
    Published