Synthesis and application of chiral bicyclic proline's derivatives for the synthesis of enantiodifferenting, traceless, triazine coupling reagenta

2012/07/N/ST5/01883

Keywords

Descriptors

  • ST5_23: Chemia organiczna
  • ST5_16: Chemia biologiczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Politechnika Łódzka, Wydział Chemiczny

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Maria Kasperowicz-Frankowska

Number of co-investigators in the project: 3

Call

PRELUDIUM 4 – announced on 2012-09-15

Amount awarded
49 600 PLN
Project start date
2013-09-02
Project end date
2014-09-01
Project duration
12 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Kolumny do chromatografii z chiralnym wypełnieniem (2 pcs). Cost: 8 000 PLN
  2. Zestaw kolumn do chromatografii obejmujący: chiralną kolumnę do chromatografii gazowej (z możliwością wykorzystania do GC-MS) oraz achiralną kolumnę do HPLC. Cost: 5 603 PLN
  3. achiralna kolumna do HPLC. Cost: 2 298 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Synthesis of Chiral Triazine Coupling Reagents Based on Esters of N-Alkylproline and Their Application in The Enantioselective Incorporation D or L Amino Acid Residue Directly From Racemic Substrate

    Authors:
    Katarzyna Kasperowicz-Frankowska, Anna Gzik, Michał Dziemidkiewicz, Beata Kolesińska, Zbigniew J. Kamiński
    Academic press:
    Acta Poloniae Pharm. Drug Res. (year: 2014, volume: 71(6), pages: 994-1003), Publisher: Polskie Towarzystwo Farmaceutyczne
    Status:
    Published
    DOI:
    link to the publication
  2. 1,3-oxazolidin-5-ones derived from proline as a chiral components in the synthesis of predictive enantioselective coupling reagents.

    Authors:
    Katarzyna Kasperowicz-Frankowska, Beata Kolesińska, Anna Gzik, Konrad Jastrząbek, Zbigniew J. Kamiński,
    Status:
    Accepted for publication

Articles in post-conference publications (2)

  1. Synthesis and application of chiral bicyclic proline's derivatives for the synthesis of enantiodifferenting, traceless triazine coupling reagents

    Authors:
    Kasperowicz-Frankowska, K.; Dziemidkiewicz, M.; Kolesińska, B.; Kamiński, Z.J.
    Conference:
    22nd Polish Peptide Symposium (year: 2013, pages: 95), Publisher: Oficyna Wydawnicza Politechniki Wrocławskiej
    Date:
    conference 1-5 Września 2013
    Status:
    Published
    DOI:
    link to the publication
  2. 1,3-Oxazolidin-5-ones as Chiral components in the synthesis of traceless enantioselective reagents

    Authors:
    Kasperowicz-Frankowska, K.; Jastrząbek, K.; Kolesińska, B.; Kamiński, Z.J.
    Conference:
    IX MULTIDYSCYPLINARNA KONFERENCJA NAUKI O LEKU (year: 2014, pages: 27), Publisher: pieleszek reaserch
    Date:
    conference 12-14 maja 2014
    Status:
    Published
    DOI:
    link to the publication

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