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Peripheral blood mononuclear cells as a model for the neurotoxic effects of chemotherapy

2012/07/B/NZ7/04354

Keywords

Descriptors

  • NZ7_14: Farmacja, farmakoterapia, farmakologia

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Rodryg Ramlau

Number of co-investigators in the project: 6

Call

OPUS 4 – announced on 2012-09-15

Amount awarded
580 903 PLN
Project start date
2013-07-11
Project end date
2016-07-10
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. O2k-Core. Cost: 210 000 PLN
  2. czytnik mikropłytkowy Flx800, MedTek. Cost: 75 000 PLN

Information in the final report

Publication in academic press/journals (3)

  1. The Effect on Cognition of Mitochondrial Respiratory System Proteins in Peripheral Blood Mononuclear Cells in the Course of Lung Cancer

    Authors:
    Michalak S, Rybacka-Mossakowska J, Gazdulska J, Gołda-Gocka I, Ramlau R
    Academic press:
    Adv Exp Med Biol (year: 2016, volume: 2016 March 18, pages: 46034), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/5584_2016_221 – link to the publication

  2. The Markers of Glutamate Metabolism in Peripheral Blood Mononuclear Cells and Neurological Complications in Lung Cancer Patients

    Authors:
    Slawomir Michalak, Joanna Rybacka-Mossakowska, Wojciech Ambrosius, Joanna Gazdulska, Iwona Golda-Gocka, Wojciech Kozubski, Rodryg Ramlau
    Academic press:
    Disease Markers (year: 2016, volume: 2895972, pages: 46030), Publisher: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2016/2895972 – link to the publication

  3. Humoral Immune Response against Neural Antigens and Its Effects on Cognition in Lung Cancer Patients

    Authors:
    Rybacka-Mossakowska J, Ramlau R, Gazdulska J, Gołda-Gocka I, Kozubski W, Michalak S
    Academic press:
    Adv Exp Med Biol (year: 2016, volume: 42445, pages: 46034), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/5584_2016_211 – link to the publication

Articles in post-conference publications (7)

  1. Kynurenine pathway activity in peripheral blood mononuclear cells and cognitive functions in lung cancer patients

    Authors:
    Ramlau R, Michalak S, Rybacka – Mossakowska J, Gazdulska J, Gołda-Gocka I.
    Conference:
    16th World Conference on lung cancer (year: 2015, pages: P1-04-075), Publisher: International Association for the Study of Lung Cancer
    Date:
    conference 6-9.09.2015
    Status:
    Published

  2. The expression of key mitochondrial respiratory system proteins in peripheral blood mononuclear cells and cognitive impairment in lung cancer patients

    Authors:
    Michalak S, Rybacka-Mossakowska J, Gazdulska J, Gołda-Gocka I, Ramlau R.
    Conference:
    26th Bilateral Symposium Poznan-Halle From Molecular Medicine to Public Health - Translational Research in Cardiovascular Medicine and Oncology. (year: 2015, pages: 38-39), Publisher: Martn Luther University Halle-Wittenberg
    Date:
    conference October 23rd - 25th 2015
    Status:
    Published

  3. The effect kynurenine metabolism in peripheral blood mononuclear cells on cognition in lung cancer patients

    Authors:
    Michalak S, Rybacka-Mossakowska J, Gazdulska J, Gołda-Gocka I, Ramlau R
    Conference:
    26th Bilateral Symposium Poznan-Halle From Molecular Medicine to Public Health - Translational Research in Cardiovascular Medicine and Oncology (year: 2015, pages: 36-37), Publisher: Martin Luther University Halle - Wittenberg
    Date:
    conference October 23rd - 25th 2015
    Status:
    Published

  4. The effect of mitochondrial respiratory system in peripheral blood mononuclear cells on cognition during the course of lung cancer

    Authors:
    Michalak S, Rybacka – Mossakowska J, Gazdulska J, Gołda-Gocka I, Ramlau R.
    Conference:
    Advances in pneumology - International Conference (year: 2015, pages: 1), Publisher: Conventus Congressmanagement & Marketing GmbH
    Date:
    conference 6-7.11.2015
    Status:
    Published

  5. Mitochondrial status in peripheral blood mononuclear cells in relation to cognitive impairment in lung cancer patients

    Authors:
    Ramlau R, Michalak S, Rybacka – Mossakowska J, Gazdulska J, Gołda-Gocka I.
    Conference:
    16th World Conference on lung cancer (year: 2015, pages: P1-04-054), Publisher: International Association for the Study of Lung Cancer
    Date:
    conference 6-9.09.2015
    Status:
    Published

  6. Przydatność platformy PEBL w ocenie zaburzeń funkcji poznawczych w przebiegu choroby nowotworowej

    Authors:
    Rybacka – Mossakowska J, Świniuch D, Gazdulska J, Litwiniuk M, Ramlau R, Kozubski W, Michalak S.
    Conference:
    XXII Zjazd Polskiego Towarzystwa Neurologicznego (year: 2014, pages: 8), Publisher: Skolamed
    Date:
    conference 3-6.09.2014
    Status:
    Published

  7. Heat shock protein 70 and lysosomal-associated membrane protein 2A expression in peripheral blood mononuclear cells and cognitive functions in lung cancer patients

    Authors:
    J.Rybacka – Mossakowska, S.Michalak, J.Gazdulska, I.Gołda-Gocka, R.Ramlau
    Conference:
    5th International Conference Advances in Neuroimmunology (year: 2016, pages: 1), Publisher: Divisia
    Date:
    conference 17-18 June 2016
    Status:
    Published

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