Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Peripheral blood mononuclear cells as a model for the neurotoxic effects of chemotherapy

2012/07/B/NZ7/04354

Keywords:

chemobrain chemotherapy nervous system peripheral blood mononuclear cells

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Rodryg Ramlau 

Number of co-investigators in the project: 6

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 580 903 PLN

Project start date (Y-m-d): 2013-07-11

Project end date (Y-m-d): 2016-07-10

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. O2k-Core (210 000 PLN)
  2. czytnik mikropłytkowy Flx800, MedTek (75 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (7)
  1. The Effect on Cognition of Mitochondrial Respiratory System Proteins in Peripheral Blood Mononuclear Cells in the Course of Lung Cancer
    Authors:
    Michalak S, Rybacka-Mossakowska J, Gazdulska J, Gołda-Gocka I, Ramlau R
    Academic press:
    Adv Exp Med Biol (rok: 2016, tom: 2016 March 18, strony: 45303), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/5584_2016_221 - link to the publication
  2. Humoral Immune Response against Neural Antigens and Its Effects on Cognition in Lung Cancer Patients
    Authors:
    Rybacka-Mossakowska J, Ramlau R, Gazdulska J, Gołda-Gocka I, Kozubski W, Michalak S
    Academic press:
    Adv Exp Med Biol (rok: 2016, tom: 42445, strony: 45303), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/5584_2016_211 - link to the publication
  3. The Markers of Glutamate Metabolism in Peripheral Blood Mononuclear Cells and Neurological Complications in Lung Cancer Patients
    Authors:
    Slawomir Michalak, Joanna Rybacka-Mossakowska, Wojciech Ambrosius, Joanna Gazdulska, Iwona Golda-Gocka, Wojciech Kozubski, Rodryg Ramlau
    Academic press:
    Disease Markers (rok: 2016, tom: 2895972, strony: 45299), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2016/2895972 - link to the publication
  1. The effect kynurenine metabolism in peripheral blood mononuclear cells on cognition in lung cancer patients
    Authors:
    Michalak S, Rybacka-Mossakowska J, Gazdulska J, Gołda-Gocka I, Ramlau R
    Conference:
    26th Bilateral Symposium Poznan-Halle "From Molecular Medicine to Public Health - Translational Research in Cardiovascular Medicine and Oncology" (rok: 2015, ), Wydawca: Martin Luther University Halle - Wittenberg
    Data:
    konferencja October 23rd - 25th 2015
    Status:
    Published
  2. The effect of mitochondrial respiratory system in peripheral blood mononuclear cells on cognition during the course of lung cancer
    Authors:
    Michalak S, Rybacka – Mossakowska J, Gazdulska J, Gołda-Gocka I, Ramlau R.
    Conference:
    Advances in pneumology - International Conference (rok: 2015, ), Wydawca: Conventus Congressmanagement & Marketing GmbH
    Data:
    konferencja 6-7.11.2015
    Status:
    Published
  3. Heat shock protein 70 and lysosomal-associated membrane protein 2A expression in peripheral blood mononuclear cells and cognitive functions in lung cancer patients
    Authors:
    J.Rybacka – Mossakowska, S.Michalak, J.Gazdulska, I.Gołda-Gocka, R.Ramlau
    Conference:
    5th International Conference Advances in Neuroimmunology (rok: 2016, ), Wydawca: Divisia
    Data:
    konferencja 17-18 June 2016
    Status:
    Published
  4. Kynurenine pathway activity in peripheral blood mononuclear cells and cognitive functions in lung cancer patients
    Authors:
    Ramlau R, Michalak S, Rybacka – Mossakowska J, Gazdulska J, Gołda-Gocka I.
    Conference:
    16th World Conference on lung cancer (rok: 2015, ), Wydawca: International Association for the Study of Lung Cancer
    Data:
    konferencja 6-9.09.2015
    Status:
    Published
  5. Mitochondrial status in peripheral blood mononuclear cells in relation to cognitive impairment in lung cancer patients
    Authors:
    Ramlau R, Michalak S, Rybacka – Mossakowska J, Gazdulska J, Gołda-Gocka I.
    Conference:
    16th World Conference on lung cancer (rok: 2015, ), Wydawca: International Association for the Study of Lung Cancer
    Data:
    konferencja 6-9.09.2015
    Status:
    Published
  6. Przydatność platformy PEBL w ocenie zaburzeń funkcji poznawczych w przebiegu choroby nowotworowej
    Authors:
    Rybacka – Mossakowska J, Świniuch D, Gazdulska J, Litwiniuk M, Ramlau R, Kozubski W, Michalak S.
    Conference:
    XXII Zjazd Polskiego Towarzystwa Neurologicznego (rok: 2014, ), Wydawca: Skolamed
    Data:
    konferencja 3-6.09.2014
    Status:
    Published
  7. The expression of key mitochondrial respiratory system proteins in peripheral blood mononuclear cells and cognitive impairment in lung cancer patients
    Authors:
    Michalak S, Rybacka-Mossakowska J, Gazdulska J, Gołda-Gocka I, Ramlau R.
    Conference:
    26th Bilateral Symposium Poznan-Halle "From Molecular Medicine to Public Health - Translational Research in Cardiovascular Medicine and Oncology". (rok: 2015, ), Wydawca: Martn Luther University Halle-Wittenberg
    Data:
    konferencja October 23rd - 25th 2015
    Status:
    Published