Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of Rap proteins in regulation of mTOR function

2012/07/E/NZ3/00503

Keywords:

mTOR Rab GTPases neuronal development. neuronal plasticity membrane trafficking

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Jaworski 

Number of co-investigators in the project: 4

Call: SONATA BIS 2 - announced on 2012-09-15

Amount awarded: 1 500 000 PLN

Project start date (Y-m-d): 2013-06-25

Project end date (Y-m-d): 2018-08-24

Project duration:: 62 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw do równoczesnej elekterforezy i transferu nistedndardowej liczby próbek białkowych (15 000 PLN)
  2. Mikrowirówka laboratoryjna z chłodzeniem (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches
    Authors:
    Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J.
    Academic press:
    IUBMB Life (rok: 2016, tom: 68(12), strony: 955-962), Wydawca: John Wiley & Sons, Inc.
    Status:
    Published
    DOI:
    10.1002/iub.1579 - link to the publication
  2. ESCRT Proteins Control the Dendritic Morphology of Developing and Mature Hippocampal Neurons.
    Authors:
    Firkowska M., Macias M., Jaworski J.
    Academic press:
    Molecular Neurobiology (rok: 2019, tom: 56(7), strony: 4866-4879), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-018-1418-9 - link to the publication
  3. GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation.
    Authors:
    Gozdz A., Nikolaienko O., Urbanska M., Cymerman IA., Sitkiewicz E., Blazejczyk M., Dadlez M., Bramham CR., Jaworski J.
    Academic press:
    Front Mol Neurosci. (rok: 2017, tom: 10, strony: 192), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fnmol.2017.00192 - link to the publication
  4. Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites.
    Authors:
    Lipka J, Kapitein LC, Jaworski J, Hoogenraad CC.
    Academic press:
    EMBO J. (rok: 2016, tom: 35(3), strony: 302-18), Wydawca: EMBO
    Status:
    Published
    DOI:
    10.15252/embj.201592929 - link to the publication
  5. ZBP1 phosphorylation at serine 181 regulates its dendritic transport and the development of dendritic trees of hippocampal neurons.
    Authors:
    3.Urbanska AS., Janusz-Kaminska A., Switon K., Hawthorne AL., Perycz M., Urbanska M., Bassell GJ., Jaworski J.
    Academic press:
    Scientific Reports (rok: 2017, tom: 7(1), strony: 1876), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-017-01963-2 - link to the publication
  6. Molecular neurobiology of mTOR
    Authors:
    Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J.
    Academic press:
    Neuroscience (rok: 2017, tom: 341, strony: 112-153), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuroscience.2016.11.017 - link to the publication

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