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Information on the principal investigator and host institution

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Hypoxia influence on human muscle stem cells genetically modified with proangiogenic factors: VEGF/FGF and PlGF.

2012/07/N/NZ3/01687

Keywords:

stem cells angiogenesis hypoxia

Descriptors:

  • NZ3_8: Stem cell biology
  • NZ3_1: Cell biology
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Genetyki Człowieka PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Agnieszka Zimna 

Number of co-investigators in the project: 2

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 97 305 PLN

Project start date (Y-m-d): 2013-07-10

Project end date (Y-m-d): 2016-01-09

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. Hypoxia-Inducible Factor-1 in Physiological and Pathophysiological Angiogenesis: Applications and Therapies.
    Authors:
    Zimna A., Kurpisz M.
    Academic press:
    Biomed Research International (rok: 2015, tom: 2015, strony: 45304), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2015/549412 - link to the publication
  2. Human myoblast transplantation in mice infarcted heart alters the expression profile of cardiac genes associated with left ventricle remodeling
    Authors:
    Wiernicki B., Rozwadowska N., Malcher A., Kolanowski T., Zimna A., Rugowska A., Kurpisz M.
    Academic press:
    International Journal of Cardiology (rok: 2016, tom: 202, strony: 710–721), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijcard.2015.09.115. - link to the publication
  3. Biological and pro-angiogenic properties of genetically modified human primary myoblasts overexpressing Placental Growth Factor- in vitro and in vivo studies
    Authors:
    Zimna A., Wiernicki B., Kolanowski T., Rozwadowska N., Malcher A., Labedz W., Trzeciak T., Chojnacka K., Bednarek-Rajewska K., Majewski P., Kurpisz M.
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2018, tom: Vol 66 Issue 2, strony: 145-159), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00005-017-0486-2 - link to the publication
  4. Influence of hypoxia prevailing in post-infarction heart on proangiogenic gene expression and biological features of human myoblast cells applied as a pro-regenerative therapeutic tool.
    Authors:
    Zimna A., Wiernicki B., Kolanowski T., Malcher A. , Rozwadowska N., Labedz W., Kubaszewski L., Kurpisz M.
    Academic press:
    Journal of Physiology and Pharmacology (rok: 2018, ), Wydawca: Journal of Physiology and Pharmacology
    Status:
    Submitted
    DOI:
    brak - link to the publication

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