Projects funded by the NCN
Synthesis and biological studies of conjugates formed by peptide dendrimers and natural polyphenols and their analogs
2012/07/B/ST5/01941
Keywords:
dendrimers natural polyphenols antioxidants antiproliferative antiaggregatory
Descriptors:
- ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
- ST5_16:
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Instytut Chemii Organicznej PAN
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 8
Call: OPUS 4 - announced on 2012-09-15
Amount awarded: 535 000 PLN
Project start date (Y-m-d): 2013-06-26
Project end date (Y-m-d): 2016-10-25
Project duration:: 40 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Oprogramowanie MSOffice (300 PLN)
- Zestaw komputerowy z monitorem.
- 50 ml pumphead to HPLC (4 200 PLN)
- Liofilizator.
- ChemBioDraw.
- Wyparka z pompą (35 000 PLN)
- ChemDraw Ultra (1 500 PLN)
- Kolumny analityczne i półpreparatywne o odwróconych fazach do posiadanej aparatury HPLC pracujące w dużym zakresie pH (4 szt.) (20 000 PLN)
- Rożek ultradżwiękowy (10 000 PLN)
Information in the final report
- Publication in academic press/journals (5)
- Book publications / chapters in book publications (1)
- Chlorogenic Acids Mimics - Synthesis, Structure and Antioxidant ActivityAuthors:Magdalena Szewczyk, Maja Morawiak, Aleksandra Narczyk Zbigniew Pakulski, Zofia Urbanczyk-LipkowskaAcademic press:Journal of Chemistry and Biochemistry (rok: 2018, tom: 6, strony: 28-37), Wydawca: American Research Institute for Policy DevelopmentStatus:PublishedDOI:10.15640/jcb.v6n1a4 - link to the publication
- Kurkumina - nadzieja w prewencji i leczeniu chorób neurodegeneracyjnychAuthors:E. Łukasik, Z. Urbanczyk-LipkowskaAcademic press:Gazeta Farmaceutyczna (rok: 2014, tom: 12(268), strony: 24-26), Wydawca: KwadrygaStatus:PublishedDOI:brak - link to the publication
- Molecular antioxidant properties and in vitro cell toxicity of the p-aminobenzoic acid (PABA) functionalized peptide dendrimersAuthors:Marta Sowinska, Maja Morawiak, Marta Bochynska-Czyz, Andrzej W. Lipkowski, Elżbieta Zieminska, Barbara Zabłocka, Zofia Urbanczyk-LipkowskaAcademic press:Biomolecules (rok: 2019, tom: 9, strony: 89-111), Wydawca: MDPIStatus:PublishedDOI:10.3390/biom9030089 - link to the publication
- Interactions of rationally designed small peptide dendrons functionalised with valine or sinapic acid with α-helix and β-sheet structures of poly-L-lysine and poly-L-glutamic acidAuthors:Maja Morawiak, Magdalena Stolarska, Maciej Cieślak, Zofia Urbanczyk-LipkowskaAcademic press:Biopolymers Peptide Science (rok: 2020, tom: 112, strony: 45305), Wydawca: WileyStatus:PublishedDOI:10.1002/pep2.24155 - link to the publication
- Second generation amphiphilic polylysine dendrons inhibit glioblastoma cell proliferation without toxicity for neurons or astrocytesAuthors:Jolanta Janiszewska, Inmaculada Posadas, Pablo Játiva, Marta Bugaj-Wolukaniec, Zofia Urbanczyk-Lipkowska, Valentín CeñaAcademic press:PLOS ONE (rok: 2016, tom: 11, strony: Article Number: e0165704), Wydawca: PUBLIC LIBRARY SCIENCE, 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USAStatus:PublishedDOI:10.1371/journal.pone.0165704 - link to the publication
- Nanochemistry in drug designAuthors:Marta Sowinska, Maja Morawiak, Zofia Urbanczyk-Lipkowska and Jolanta SoleckaBook:Beta Lactams: Novel Synthetic Pathways and Applications (rok: 2017, tom: 1, strony: 311-334), Wydawca: Springer/Special Editor dr Bimal K. BanikStatus:Published