Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Identyfication of new differentally methylated regions (DMRs) in swine targeted genes using methylome analysis (MeDIP) and next generation sequencing (NGS) for improvement of somatic cell nuclear transfer (SCNT) efficiency.

2012/07/N/NZ9/02060

Keywords:

pigs DMRs DNA methylation somatic cell cloning SCNT

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Genetyki i Hodowli Zwierząt PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Maciej Grzybek 

Number of co-investigators in the project: 2

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2013-09-06

Project end date (Y-m-d): 2017-03-05

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. Epigenetics of cell fate reprogramming and its implications for neurological disorders modeling
    Authors:
    Maciej Grzybek, Aleksandra Golonko, Marta Walczak, Pawel Lisowski
    Academic press:
    Neurobiology of Disease (rok: 2017, tom: 99, strony: 84–120), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.nbd.2016.11.007 - link to the publication
  2. Evaluation of Anthelmintic Activity and Composition of Pumpkin (Cucurbita pepo L.) Seed Extracts—In Vitro and in Vivo Studies
    Authors:
    Maciej Grzybek, Wirginia Kukula-Koch, Aneta Strachecka, Aleksandra Jaworska, Andrew M. Phiri, Jerzy Paleolog, Krzysztof Tomczuk
    Academic press:
    International Journal of Molecular Sciences (rok: 2016, tom: 17, strony: 1456), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms17091456 - link to the publication
  3. Insights into the biochemical defence and methylation of the solitary bee Osmia rufa L: a foundation for examining eusociality development
    Authors:
    Aneta Strachecka; Jacek Chobotow; Jerzy Paleolog; Aleksandra Los; Michal Schulz; Dariusz Treper; Halina Kucharczyk; Maciej Grzybek
    Academic press:
    PLoS One (rok: 2017, tom: brak, strony: 45314), Wydawca: plos.org
    Status:
    Published
    DOI:
    10.1371/journal.pone.0176539 - link to the publication
  4. Methylation Genome-Wide Profiling in Lowly and Highly Efficient Somatic Cell Nuclear Transfer in Pigs
    Authors:
    Maciej Grzybek, Krzysztof Flisikowski, Tom Giles, Marta Dyjak, Rafal Ploski, Piotr Gasperowicz, Richard D Emes, Pawel Lisowski
    Academic press:
    Applied Sciences (rok: 2023, tom: 13, strony: 4798), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/app13084798 - link to the publication

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