Low level of endogenous glutathione as a cause of fever absence during infaction and inflammation
2012/07/B/NZ4/00197
Keywords
Descriptors
- NZ4_12: Inne zagadnienia pokrewne
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Uniwersytet Mikołaja Kopernika, Wydział Biologii i Ochrony Środowiska
Voivodeship: kujawsko-pomorskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
OPUS 4 – announced on 2012-09-15
- Amount awarded
- 246 760 PLN
- Project start date
- 2013-07-08
- Project end date
- 2017-12-07
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Homogenizator.
- Zestaw do utrzymywania temeratury ciała. Cost: 15 000 PLN
- sterylizator kulkowy. Cost: 4 000 PLN
- zamrażarka. Cost: 1 549 PLN
Information in the final report
Publication in academic press/journals (3)
-
Glutathione deficiency attenuates endotoxic fever in rats
- Authors:
- Wrotek S, Jedrzejewski T, Nowakowska A & Kozak W.
- Academic press:
- International Journal of Hyperthermia, (year: 2015, volume: 31(7), pages: 793-9), Publisher: Taylor & Francis
- Status:
- Published
- DOI:
- 10.3109/02656736.2015.1067333 – link to the publication
-
LPS alters pattern of sickness behavior but does not affect glutathione level in aged male rats.
- Authors:
- Wrotek S, Jedrzejewski T, Nowakowska A, Kozak W.
- Academic press:
- Biogerontology 2016 (year: 2016, volume: February, pages: 46031), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s10522-016-9636-x – link to the publication
-
Buthionine sulfoximine, a glutathione depletor, attenuates endotoxic fever and reduces IL-1b and IL-6 level in rats
- Authors:
- Sylwia Wrotek, Krzysztof Domagalsk, Tomasz Je˛drzejewski, Eliza Dec, Wiesław Kozak
- Academic press:
- Cytokine (year: 2017, volume: 90, pages: 31–37), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.cyto.2016.10.005. – link to the publication
Articles in post-conference publications (1)
-
Immunological consequences of manipulation in glutathione level
- Authors:
- Sylwia Wrotek, Tomasz Jędrzejewski, Magdalena Wolska, Wiesław Kozak
- Conference:
- The XVIth Congress of the Polish Society of Experimental and Clinical Immunology (year: 2017, pages: p.5), Publisher: Termedia Publishing House Ltd.
- Date:
- conference June 8-10,
- Status:
- Published