Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Studies on the interaction between bioactive polymers and lipid membranes

2012/07/B/ST5/00913

Keywords:

liposomes biopolymers polyelectrolytes MD simulations hyaluronic acid poly(allylamine) cryo-TEM microscopy confocal microscopy

Descriptors:

  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST5_22:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mariusz Kępczyński 

Number of co-investigators in the project: 8

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 708 000 PLN

Project start date (Y-m-d): 2013-07-02

Project end date (Y-m-d): 2016-11-01

Project duration:: 40 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. kamera do mikroskopu konfokalnego (22 140 PLN)
  2. ssak elektryczny.
  3. generator funkcyjny.
  4. mikrokalorymetr DSC (300 000 PLN)
  5. komputer PC (5 000 PLN)
  6. dysk twardy zewnętrzny, 5 sztuk.

Information in the final report

  • Publication in academic press/journals (10)
  1. Effect of Phosphatidic Acid on Biomembrane: Experimental and Molecular Dynamics Simulations Study
    Authors:
    Urszula Kwolek, Waldemar Kulig, Paweł Wydro, Maria Nowakowska, Tomasz Róg, Mariusz Kepczynski
    Academic press:
    The Journal of Physical Chemistry B (rok: 2015, tom: 119, strony: 10042-10051), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.5b03604 - link to the publication
  2. Effect of piroxicam on lipid membranes: Drug encapsulation and gastric toxicity aspects
    Authors:
    Natalia Wilkosz, Sami Rissanen, Małgorzata Cyza, Renata Szybka, Maria Nowakowska, Alex Bunker, Tomasz Róg and Mariusz Kepczynski
    Academic press:
    European Journal of Pharmaceutical Sciences (rok: 2017, tom: 100, strony: 116–125), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejps.2017.01.007 - link to the publication
  3. Interactions of Polyethylenimines with Zwitterionic and Anionic Lipid Membranes
    Authors:
    Urszula Kwolek, Dorota Jamróz, Małgorzata Janiczek, Maria Nowakowska, Paweł Wydro, Mariusz Kepczynski
    Academic press:
    Langmuir (rok: 2016, tom: 32, strony: 5004−5018), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.langmuir.6b00490 - link to the publication
  4. Effects of Membrane PEGylation on Entry and Location of Antifungal Drug Itraconazole and their Pharmacological Implications
    Authors:
    Monika Dzieciuch-Rojek, Chetan Poojari, Jan Bednar, Alex Bunker, Bartłomiej Kozik, Maria Nowakowska, Ilpo Vattulainen, Paweł Wydro, Mariusz Kepczynski, Tomasz Róg
    Academic press:
    Molecular Pharmaceutics (rok: 2017, tom: 14, strony: 1057−1070), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.molpharmaceut.6b00969 - link to the publication
  5. Growth and motility of human skin fibroblasts on multilayer strong polyelectrolyte films
    Authors:
    Magdalena Wytrwal, Paulina Koczurkiewicz, Karol Zrubek, Wiktor Niemiec, Marta Michalik, Bartłomiej Kozik, Edward Szneler, Andrzej Bernasik, Zbigniew Madeja, Maria Nowakowska, Mariusz Kepczynski
    Academic press:
    Journal of Colloid and Interface Science (rok: 2016, tom: 461, strony: 305–316), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jcis.2015.09.039 - link to the publication
  6. Synthesis and Antibacterial Properties of Quaternary Ammonium Derivative of Polyethylenimine
    Authors:
    Urszula Kwolek, Kinga Wójcik, Małgorzata Janiczek, Maria Nowakowska, Mariusz Kepczynski
    Academic press:
    Polimery (rok: 2017, tom: 62, strony: 463-468), Wydawca: Instytut Chemii Przemysłowej im. prof. Ignacego Mościckiego
    Status:
    Published
    DOI:
    10.14314/polimery.2017.0463 - link to the publication
  7. Effect of Polycation Structure on Interaction with Lipid Membranes
    Authors:
    Natalia Wilkosz, Dorota Jamróz, Wojciech Kopeć, Keita Nakai, Shin-ichi Yusa, Magdalena Wytrwal-Sarna, Jan Bednar, Maria Nowakowska, Mariusz Kepczynski
    Academic press:
    The Journal of Physical Chemistry B (rok: 2017, tom: 121, strony: 7318−7326), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.7b05248 - link to the publication
  8. Interactions of serum with polyelectrolyte-stabilized liposomes:Cryo-TEM studies
    Authors:
    Magdalena Wytrwal, Jan Bednar, Maria Nowakowska,Paweł Wydro, Mariusz Kepczynski
    Academic press:
    Colloids and Surfaces B: Biointerfaces (rok: 2014, tom: 120, strony: 152-159), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2014.02.040 - link to the publication
  9. PEGylated Liposomes as Carriers of Hydrophobic Porphyrins
    Authors:
    Monika Dzieciuch, Sami Rissanen, Natalia Szydłowska, Alex Bunker, Marta Kumorek, Dorota Jamróz, Ilpo Vattulainen, Maria Nowakowska, Tomasz Róg, Mariusz Kepczynski
    Academic press:
    The Journal of Physical Chemistry B (rok: 2015, tom: 119, strony: 6646−6657), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.5b01351 - link to the publication
  10. Functionalized lipids and surfactants for specific applications
    Authors:
    Mariusz Kepczynski, Tomasz Rog
    Academic press:
    Biochimica Biophysica Acta – Biomembranes (rok: 2016, tom: 1858, strony: 2362–2379), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2016.02.038 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy