Pronucloetides - a pathway to cellular DNA sensitization to ionizing radiation
2012/07/N/ST5/01877
Keywords
Descriptors
- ST5_11: Synteza biomateriałów
- ST5_16: Chemia biologiczna
- ST5_23: Chemia organiczna
Panel
ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution
Uniwersytet Gdański, Wydział Chemii
Voivodeship: pomorskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
PRELUDIUM 4 – announced on 2012-09-15
- Amount awarded
- 148 717 PLN
- Project start date
- 2013-08-20
- Project end date
- 2016-08-19
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Inkubator CO2 ( Binder C 150 – Biotech: www.biotech-polska.pl). Cost: 24 477 PLN
- Komora laminarna (np. Biosan UVC/T-B-AR - Biotech: www.biotech-polska.pl). Cost: 8 118 PLN
- Mikroskop (np. OPTICA B-353PL – Biotech: www.biotech-polska.pl). Cost: 4 957 PLN
- Łaźnia wodna.
Information in the final report
Publication in academic press/journals (3)
-
5-Thiocyanato-20-deoxyuridine as a possible radiosensitizer: electron-induced formation of uracil-C5-thiyl radical and its dimerization
- Authors:
- Magdalena Zdrowowicz, Lidia Chomicz, Michał Żyndul, Paweł Wityk, Janusz Rak,Tyler J. Wiegand, Cameron G. Hanson, Amitava Adhikary, Michael D. Sevilla
- Academic press:
- Physical Chemistry Chemical Physics (year: 2015, volume: 17, pages: 16907), Publisher: Royal Society Of Chemistry
- Status:
- Published
- DOI:
- 10.1039/c5cp02081f – link to the publication
-
How to Find Out Whether a 5-Substituted Uracil Could Be a Potential DNA Radiosensitizer
- Authors:
- Lidia Chomicz, Magdalena Zdrowowicz, Franciszek Kasprzykowski, Janusz Rak, Angela Buonaugurio, Yi Wang, Kit H. Bowen
- Academic press:
- The Journal of Physical Chemistry Letters (year: 2013, volume: 4 (17), pages: 2853-2857), Publisher: ACS Publications
- Status:
- Published
- DOI:
- 10.1021/jz401358w – link to the publication
-
Mechanisms of Damage to DNA Labeled with Electrophilic Nucleobases Induced by Ionizing or UV Radiation
- Authors:
- Janusz Rak, Lidia Chomicz, Justyna Wiczk, Kinga Westphal, Magdalena Zdrowowicz, Paweł Wityk, Michał Żyndul, Samanta Makurat, Łukasz Golon
- Academic press:
- The Journal of Physical Chemistry B (year: 2015, volume: 119, pages: 8227-8238), Publisher: American Chemical Society
- Status:
- Published
- DOI:
- 10.1021/acs.jpcb.5b03948 – link to the publication