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Information on the principal investigator and host institution

Information of the project and the call

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Effect of BDE-47 and its hydroxylated metabolites on selected parameters related to the progression of ovarian cancer.

2012/07/N/NZ7/01141

Keywords:

ovarian cancer BDE-47 PBDEs metabolites proliferation apoptosis

Descriptors:

  • NZ7_2: Environment and health risks

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi, Instytut Zoologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Karpeta 

Number of co-investigators in the project: 2

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 99 970 PLN

Project start date (Y-m-d): 2013-09-13

Project end date (Y-m-d): 2015-10-12

Project duration:: 25 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Differences in the mechanisms of action of BDE-47 and its metabolites on OVCAR-3 and MCF-7 cell apoptosis.
    Authors:
    Anna Karpeta, Ewa Łucja Gregoraszczuk
    Academic press:
    Journal of Applied Toxicology (rok: 2017, tom: 37 (4), strony: 426-435), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/jat.3375 - link to the publication
  2. Different mechanisms of action of 2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) and its metabolites (5-OH-BDE-47 and 6-OH-BDE-47) on cell proliferation in OVCAR-3 ovarian cancer cells and MCF-7 breast cancer cells.
    Authors:
    Anna Karpeta, Anna Maniecka, Ewa Łucja Gregoraszczuk
    Academic press:
    Journal of Applied Toxicology (rok: 2016, tom: 36(12), strony: 1558-1567), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/jat.3316 - link to the publication
  1. Wpływ BDE-47 i jego hydroksylowanych metabolitów (5-OH-BDE-47 i 6-OH-BDE-47) na proliferację i apoptozę komórek OVCAR-3
    Authors:
    Karpeta A., Gregoraszczuk E.Ł.
    Conference:
    VII Zjazd Towarzystwa Biologii Rozrodu (rok: 2014, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 11-13 września
    Status:
    Published

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