Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The role of AS160 protein in the myocytes fatty acid transport and subsequent development of insulin resistance

2012/07/N/NZ3/01615

Keywords:

AS160 FAT/CD36 FABPpm FATP1 GLUT4 insulin resistance skeletal muscle

Descriptors:

  • NZ3_2: Cell physiology
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Medyczny w Białymstoku

woj. podlaskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Agnieszka Mikłosz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 98 540 PLN

Project start date (Y-m-d): 2013-07-29

Project end date (Y-m-d): 2016-03-28

Project duration:: 32 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  1. Challenging of AS160/TBC1D4 Alters Intracellular Lipid milieu in L6 Myotubes Incubated With Palmitate.
    Authors:
    Agnieszka Mikłosz, Bartłomiej Łukaszuk, Małgorzata Żendzian-Piotrowska, Justyna Brańska-Januszewska, Halina Ostrowska, Adrian Chabowski
    Academic press:
    Journal of Cellular Physiology (rok: 2017, tom: 232, strony: 2373-2386), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/jcp.25632. - link to the publication
  2. The Role of PGC-1α in the Development of Insulin Resistance in Skeletal Muscle - Revisited.
    Authors:
    Bartłomiej Łukaszuk, Krzysztof Kurek, Agnieszka Mikłosz, Małgorzata Żendzian-Piotrowska, Adrian Chabowski
    Academic press:
    Cellular Physiology and Biochemistry (rok: 2015, tom: 37, strony: 2288-2296), Wydawca: S. Karger AG, Basel
    Status:
    Published
    DOI:
    10.1159/000438584 - link to the publication
  3. Modest Decrease in Pgc1α Results in TAG Accumulation but not in Insulin Resistance in L6 Myotubes
    Authors:
    Bartlomiej Lukaszuk, Agnieszka Miklos,z Adrian Chabowsk,i Jan Górski
    Academic press:
    Cellular Physiology and Biochemistry (rok: 2015, tom: 35, strony: 1609-1622), Wydawca: S. Karger AG, Basel
    Status:
    Published
    DOI:
    10.1159/000373975 - link to the publication
  4. The Effects of AS160 Modulation on Fatty Acid Transporters Expression and Lipid Profile in L6 Myotubes.
    Authors:
    Agnieszka Mikłosz, Bartłomiej Łukaszuk, Małgorzata Żendzian-Piotrowska, Krzysztof Kurek, Adrian Chabowski
    Academic press:
    Cellular Physiology and Biochemistry (rok: 2016, tom: 38, strony: 267-282), Wydawca: S. Karger AG, Basel
    Status:
    Published
    DOI:
    10.1159/000438628 - link to the publication

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