Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The infuence of chosen ellagitannins on functions of human neutrophils the context of prevention and treatment of oral cavity dieseases

2012/07/N/NZ7/01136

Keywords:

ellagitannins periodontosis gingivitis oral cavity dieseases neutrophils

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_12: Prevention of human diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Sebastian Granica 

Number of co-investigators in the project: 3

Call: PRELUDIUM 4 - announced on 2012-09-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2013-07-11

Project end date (Y-m-d): 2015-07-10

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zakup zestawu elektronicznych pipet jedno- i wielokanałowych. (17 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (3)
  1. Contribution of C-glucosidic ellagitannins to Lythrum salicaria L. influence on pro-inflammatory functions of human neutrophils
    Authors:
    Jakub P. Piwowarski, Anna K. Kiss
    Academic press:
    Journal of Natural Medicines (rok: 2015, tom: 69, strony: 100-110), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11418-014-0873-5 - link to the publication
  2. Secondary metabolites from roots of Geum urbanum L.
    Authors:
    Jakub P. Piwowarski, Sebastian Granica, Michał Kosiński, Anna K. Kiss
    Academic press:
    Biochemical Systematics and Ecology (rok: 2014, tom: 53, strony: 46-50), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bse.2013.12.029 - link to the publication
  3. Effects of Geum urbanum L. root extracts and its constituents on polymorphonuclear leucocytes functions. Significance in periodontal diseases.
    Authors:
    Sebastian Granica, Agnieszka Kłębowska, Michał Kosiński, Jakub P. Piwowarski, Marta Dudek, Sławomir Kaźmierski, Anna K. Kiss
    Academic press:
    Journal of Ethnopharmacology (rok: 2016, tom: 188, strony: 45303), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jep.2016.04.030 - link to the publication
  4. Ellagitannins modulate the inflammatory response of human neutrophils ex vivo.
    Authors:
    Sebastian Granica, Jakub P. Piwowarski, Anna K. Kiss
    Academic press:
    Phytomedicine (rok: 2015, tom: 22, strony: 1215-1222), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.004 - link to the publication
  1. Isolation and identification of tannins from domestic plant materials and their infuence on release of elastase from stimulated human neutrophils
    Authors:
    Piwowarski, J. P.; Granica S.; Kiss, A.K.
    Conference:
    9th International Symposium on Chromatography of Natural Products (rok: 2014, ), Wydawca: Medical University of Lublin
    Data:
    konferencja 26.05.2014-29.05.2014
    Status:
    Published
  2. Isolation of tannins from Agrimonia eupatoria, Lythrum salicaria and Geum urbanum and their influence on the release of elastase from stimulated human neutrophils – structure-activity studies
    Authors:
    Granica, S.; Piwowarski, J.P.; Kiss, A.K.
    Conference:
    62st International Congress and Annual Meeting of the GA (rok: 2014, ), Wydawca: Thieme
    Data:
    konferencja 31.08.2014-04.09.2014
    Status:
    Published
    DOI:
    link to the publication
  3. The influence of tannins on the human neutrophils' pro-inflammatory mediators.
    Authors:
    Granica, S.; Piowarski, J.P.; Kiss, A. K.
    Conference:
    63rd International Congress and Annual Meeting of the GA (rok: 2015, ), Wydawca: Planta Medica, Thieme
    Data:
    konferencja 23.08.2015-26.08.2015
    Status:
    Published
    DOI:
    link to the publication

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