The infuence of chosen ellagitannins on functions of human neutrophils the context of prevention and treatment of oral cavity dieseases

2012/07/N/NZ7/01136

Keywords

Descriptors

  • NZ7_14: Farmacja, farmakoterapia, farmakologia
  • NZ7_12: Prewencja chorób człowieka

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Sebastian Granica

Number of co-investigators in the project: 3

Call

PRELUDIUM 4 – announced on 2012-09-15

Amount awarded
100 000 PLN
Project start date
2013-07-11
Project end date
2015-07-10
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Zakup zestawu elektronicznych pipet jedno- i wielokanałowych.. Cost: 17 000 PLN

Information in the final report

Publication in academic press/journals (4)

  1. Secondary metabolites from roots of Geum urbanum L.

    Authors:
    Jakub P. Piwowarski, Sebastian Granica, Michał Kosiński, Anna K. Kiss
    Academic press:
    Biochemical Systematics and Ecology (year: 2014, volume: 53, pages: 46-50), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bse.2013.12.029 – link to the publication
  2. Ellagitannins modulate the inflammatory response of human neutrophils ex vivo.

    Authors:
    Sebastian Granica, Jakub P. Piwowarski, Anna K. Kiss
    Academic press:
    Phytomedicine (year: 2015, volume: 22, pages: 1215-1222), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.phymed.2015.10.004 – link to the publication
  3. Effects of Geum urbanum L. root extracts and its constituents on polymorphonuclear leucocytes functions. Significance in periodontal diseases.

    Authors:
    Sebastian Granica, Agnieszka Kłębowska, Michał Kosiński, Jakub P. Piwowarski, Marta Dudek, Sławomir Kaźmierski, Anna K. Kiss
    Academic press:
    Journal of Ethnopharmacology (year: 2016, volume: 188, pages: 46034), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jep.2016.04.030 – link to the publication
  4. Contribution of C-glucosidic ellagitannins to Lythrum salicaria L. influence on pro-inflammatory functions of human neutrophils

    Authors:
    Jakub P. Piwowarski, Anna K. Kiss
    Academic press:
    Journal of Natural Medicines (year: 2015, volume: 69, pages: 100-110), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s11418-014-0873-5 – link to the publication

Articles in post-conference publications (3)

  1. The influence of tannins on the human neutrophils' pro-inflammatory mediators.

    Authors:
    Granica, S.; Piowarski, J.P.; Kiss, A. K.
    Conference:
    63rd International Congress and Annual Meeting of the GA (year: 2015, pages: PM-25), Publisher: Planta Medica, Thieme
    Date:
    conference 23.08.2015-26.08.2015
    Status:
    Published
    DOI:
    link to the publication
  2. Isolation and identification of tannins from domestic plant materials and their infuence on release of elastase from stimulated human neutrophils

    Authors:
    Piwowarski, J. P.; Granica S.; Kiss, A.K.
    Conference:
    9th International Symposium on Chromatography of Natural Products (year: 2014, pages: 112/P-42), Publisher: Medical University of Lublin
    Date:
    conference 26.05.2014-29.05.2014
    Status:
    Published
  3. Isolation of tannins from Agrimonia eupatoria, Lythrum salicaria and Geum urbanum and their influence on the release of elastase from stimulated human neutrophils – structure-activity studies

    Authors:
    Granica, S.; Piwowarski, J.P.; Kiss, A.K.
    Conference:
    62st International Congress and Annual Meeting of the GA (year: 2014, pages: P1L26), Publisher: Thieme
    Date:
    conference 31.08.2014-04.09.2014
    Status:
    Published
    DOI:
    link to the publication

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