Role of tumor necrosis factor (TNF) in regulation of pain reaction.
2012/05/B/NZ4/02385
Keywords
Descriptors
- NZ4_7: Neurofizjologia
- NZ4_9: Neurobiologia systemowa
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Warszawski Uniwersytet Medyczny, I Wydział Lekarski
Voivodeship: mazowieckie
Principal investigator (from the host institution)
dr hab. Ewa Zuzanna Bałkowiec-Iskra
Number of co-investigators in the project: 5
Call
OPUS 3 – announced on 2012-03-15
- Amount awarded
- 500 266 PLN
- Project start date
- 2013-02-05
- Project end date
- 2019-02-04
- Project duration
- 72 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (6)
-
Inhibition of TNF reduces mechanical orofacial hyperalgesia induced by Complete Freund's Adjuvant by a TRPV1-dependent mechanism in mice
- Authors:
- Krzysztof Lis, Tomasz Grygorowicz, Agnieszka Cudna, David E. Szymkowski, Ewa Bałkowiec-Iskra
- Academic press:
- Pharmacological Reports (year: 2017, volume: 69, pages: 1380-1385), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.pharep.2017.05.013 – link to the publication
-
Targeting of calcitonin gene-related peptide action as a new strategy for migraine treatment.
- Authors:
- Kuzawińska O, Lis K, Cessak G, Mirowska-Guzel D, Bałkowiec-Iskra E.
- Academic press:
- Neurologia i Neurochirurgia Polska (year: 2016, volume: 50, pages: 463-467), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.pjnns.2016.07.012 – link to the publication
-
GENDER DIFFERENCES IN THE NEUROCHEMICAL RESPONSE OF TRIGEMINAL GANGLION NEURONS TO PERIPHERAL INFLAMMATION IN MICE.
- Authors:
- Olga Kuzawińska, Krzysztof Lis, Agnieszka Cudna, Ewa Bałkowiec-Iskra
- Academic press:
- Acta Neurobiologiae Experimentalis (year: 2014, volume: 74, pages: 227-232), Publisher: Instytut Biologii Doświadczalnej im. M. Nenckiego
- Status:
- Published
-
Tumor necrosis factor inhibitors – State of Knowledge
- Authors:
- Lis K., Kuzawińska O.,Bałkowiec-Iskra E.
- Academic press:
- Archives of Medical Science (year: 2014, volume: 10, pages: 1175-1185), Publisher: Termedia
- Status:
- Published
- DOI:
- 10.5114/aoms.2014.47827. – link to the publication
-
The role of the CGRP in the pathogenesis and treatment of migraine
- Authors:
- Olga Kuzawinska, Krzysztof Lis, Grzegorz Cessak, Ewa Bałkowiec-Iskra
- Academic press:
- Farmakoterapia w Psychiatrii i Neurologii (year: 2015, volume: 31, pages: 127-140), Publisher: Instytut Psychiatrii i Neurologii
- Status:
- Published
- DOI:
- 10.17393/fpn.2015.10.001 – link to the publication
-
TNF inhibitors – mechanisms of action, approved and off-label indications
- Authors:
- Grzegorz Cessak , Agnieszka Burda , Olga Kuzawińska, Krzysztof Lis, Marcin Wojnar, Dagmara Mirowska-Guzel, Ewa Bałkowiec-Iskra
- Academic press:
- Pharmacological Reports (year: 2014, volume: 66, pages: 836-844), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.pharep2014.05.004 – link to the publication
Articles in post-conference publications (7)
-
Obwodowa reakcja zapalna indukowana CFA powoduje zmiany neurochemiczne w neuronach zwoju trójdzielnego
- Authors:
- Bałkowiec-Iskra E, Kuzawinska O, Cudna A, Lis K.
- Conference:
- Ból przewlekły, mechanizmy, terapia, Szkoła Zimowa IF PAN 2013 (year: 2013, pages: 162), Publisher: IF PAN
- Date:
- conference 19-22.02.2013
- Status:
- Published
-
Gender differences in the neurochemical response of trigeminal ganglion neurons to peripheral inflammation in mice
- Authors:
- Kuzawinska O., Lis K., Cudna A., Bałkowiec-Iskra E
- Conference:
- Molecular Basis of Pathology and Therapy in neurological disorders (year: 2014, pages: 341-342), Publisher: Termedia
- Date:
- conference 20-21.11.2014
- Status:
- Published
-
Peripheral inflammation affects function of trigeminal ganglion neurons.
- Authors:
- Olga Kuzawinska, Krzysztof Lis, Tomasz Grygorowicz, Agnieszka Cudna, Marta Dąbrowska, Dagmara Mirowska – Guzel, Ewa Bałkowiec-Iskra.
- Conference:
- 3.XII International Congress of Polish Neuroscience Society, 6-8.09. 2015, Gdańsk, Polska. (year: 2015, pages: S111), Publisher: -
- Date:
- conference 6-8.09. 2015
- Status:
- Published
-
INHIBITION OF TNF REDUCES MECHANICAL OROFACIAL HYPERALGESIA INDUCED BY COMPLETE FREUND'S ADJUVANT BY A TRPV1-DEPENDENT MECHANISM IN MICE
- Authors:
- Krzysztof Lis, Agnieszka Cudna, Tomasz Grygorowicz, David E. Szymkowski, Ewa Bałkowiec-Iskra
- Conference:
- 6th International Congress on Neuropathic Pain (year: 2017, pages: 184), Publisher: IASP
- Date:
- conference June 15-18
- Status:
- Published
-
Selective inhibition of TNF reduces mechanical orofacial hyperalgesia induced by Complete Freund's Adjuvant by a TRPV1-dependent mechanism in mice.
- Authors:
- Krzysztof Lis1, Agnieszka Cudna, Tomasz Grygorowicz, David E. Szymkowski, Ewa Bałkowiec-Iskra.
- Conference:
- The XVI Congress of the Polish Society of Experimental and Clinical Immunology (year: 2017, pages: 32), Publisher: PZWL
- Date:
- conference 8-10 June 2017
- Status:
- Published
-
Obwodowa reakcja zapalna wpływa na funkcje neuronów nerwu trójdzielnego u myszy
- Authors:
- Olga Kuzawińska, Krzysztof Lis, Tomasz Grygorowicz, Agnieszka Cudna, Dagmara Mirowska-Guzel, Ewa Bałkowiec-Iskra.
- Conference:
- VI Ogólnopolska Konferencja Postępu w Badaniach Biomedycznych (year: 2015, pages: 20), Publisher: -
- Date:
- conference 5-6 XII 2015
- Status:
- Published
-
Peripheral inflammation affects trigeminal neurons function in mice.
- Authors:
- Olga Kuzawinska, Krzysztof Lis, Tomasz Grygorowicz, Agnieszka Cudna, Marta Dąbrowska, Dagmara Mirowska – Guzel, Ewa Bałkowiec-Iskra.
- Conference:
- 2.XIX International Congress of The Polish Pharmacological Society, 17-19.09.2015 Swinoujście. (year: 2015, pages: 27), Publisher: Elservier
- Date:
- conference 17-19.09.2015
- Status:
- Published