Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Natural products derived from Chelidonium majus plant as potecial photosensitisers for the photodynamic therapy (PDT) of cervical cancer.

2012/05/N/NZ9/01337

Keywords:

Chelidonium majus fotouczulacze photodynamic therapy cervical cancer apoptosis

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ2_3: Proteomics
  • NZ9_9: Environmental biotechnology

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Alicja Warowicka 

Number of co-investigators in the project: 2

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 120 000 PLN

Project start date (Y-m-d): 2013-03-06

Project end date (Y-m-d): 2018-03-05

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (3)
  1. Data supporting the photodynamic properties of protoberberine compounds extracted from Chelidonium majus L.
    Authors:
    Alicja Warowicka, Łukasz Popenda, Grażyna Bartkowiak, Anna Goździcka-Józefiak
    Academic press:
    Data in Brief (rok: 2019, ), Wydawca: Elsevier
    Status:
    Submitted
  2. Major latex protein (CmMLP1) from Chelidonium majus latex accompanied by alkaloids exerts a cytotoxic effect on human cervical carcinoma cells HPV positive and negative
    Authors:
    Nawrot Robert, Warowicka Alicja, Rudzki Piotr, Musidlak Oskar, Dolata Katarzyna, Musijowski Jacek, Stolarczyk Elżbieta, Gozdzicka - Jozefiak Anna
    Academic press:
    International Journal of Biological Macromolecules (rok: 2019, tom: brak, strony: brak), Wydawca: Elsevier
    Status:
    Submitted
  3. Pharmacologically active compounds from latex-bearing plants
    Authors:
    Alicja Warowicka, Robert Nawrot, Anna Goździcka-Józefiak
    Academic press:
    Advances in Botanical Research (rok: 2020, tom: 93, strony: ), Wydawca: Elsevier
    Status:
    Accepted for publication
  4. Protoberberine compounds extracted from Chelidonium majus L. as novel natural photosensitizers for cancer therapy
    Authors:
    Warowicka Alicja, Popenda Łukasz, Bartkowiak Grażyna, Musidlak Oskar, Litowczenko Jagoda, Kuźma Dorota, Nawrot Robert, Jurga Stefan, Goździcka-Józefiak Anna
    Academic press:
    Phytomedicine (rok: 2019, tom: 64, strony: 152919), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.phymed.2019.152919 - link to the publication
  1. Identification and analysis of alakloids in various parts of Chelidonium majus (L.) using ESI and FAPA Mass Spectrometry
    Authors:
    Alicja Warowicka, G. Bartkowiak, G. Schroeder, S. Jurga, A. Goździcka-Józefiak
    Conference:
    36th Informal Meeting on Mass Spectrometry (rok: 2018, ), Wydawca: 36th Informal Meeting on Mass Spectrometry, Koszeg Hungary
    Data:
    konferencja 6-9.05.2018
    Status:
    Published
  2. Protoberberine compounds extracted from Chelidonium majus L. as novel natural photosensitizers for cervical cancer therapy
    Authors:
    Alicja Warowicka, Łukasz Popenda, Grażyna Bartkowiak, Oskar Musidlak, Jagoda Litowczenko-Cybulska, Dorota Kuźma, Robert Nawrot, Stefan Jurga, Anna Goździcka-Józefiak
    Conference:
    ICGB DNA Tumour Virus Meeting 2019 (rok: 2019, ), Wydawca: ICGB
    Data:
    konferencja 9-14.07
    Status:
    Published
  3. The effect of Chelidonium majus crude latex, as well as latex proteins and alkaloids on human papillomavirus
    Authors:
    Oskar Musidlak, Justyna Broniarczyk, Alicja Warowicka, Robert Nawrot, Anna Goździcka-Józefiak
    Conference:
    ICGB DNA Tumour Virus Meeting 2019 (rok: 2019, ), Wydawca: ICGB
    Data:
    konferencja 9-14.07
    Status:
    Published