Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Nuclear functions of mTOR in neurons

2012/05/B/NZ3/00429

Keywords:

mTOR nucleus neurons development plasticity neuropathology

Descriptors:

  • NZ3_6: Cell neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Jaworski 

Number of co-investigators in the project: 6

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 750 000 PLN

Project start date (Y-m-d): 2013-02-19

Project end date (Y-m-d): 2016-10-18

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zamrażarka niskotemeraturowa szafowa do-86 (50 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (1)
  1. Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches
    Authors:
    Switon K., Kotulska K., Janusz-Kaminska A., Zmorzynska J., Jaworski J.
    Academic press:
    IUBMB Life (rok: 2016, tom: 68(12), strony: 955-962), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/iub.1579 - link to the publication
  2. GSK3β Controls mTOR and Prosurvival Signaling in Neurons
    Authors:
    Urbanska M, Gozdz A, Macias M, Cymerman IA, Liszewska E, Kondratiuk I, Devijver H, Lechat B, Van Leuven F, Jaworski J
    Academic press:
    Mol. Neurobiol (rok: 2017, ), Wydawca: Springer International Publishing AG
    Status:
    Published
    DOI:
    10.1007/s12035-017-0823-9 - link to the publication
  3. Kainic acid induces mTORC1-dependent expression of Elmo1 in hippocampal neurons
    Authors:
    Blazejczyk M., Macias M., Korostynski M., Firkowska M., Piechota M., Skalecka A., Tempes A., Koscielny A., Urbanska M., Przewlocki R., Jaworski J.
    Academic press:
    Molecular Neurobiology (rok: 2016, ), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-016-9821-6 - link to the publication
  4. Molecular neurobiology of mTOR
    Authors:
    Switon K, Kotulska K, Janusz-Kaminska A, Zmorzynska J, Jaworski J.
    Academic press:
    Neuroscience (rok: 2016, ), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuroscience.2016.11.017 - link to the publication
  5. Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment
    Authors:
    Matylda Macias, Magdalena Blazejczyk, Paulina Kazmierska, Bartosz Caban, Agnieszka Skalecka, Bartosz Tarkowski, Anna Rodo, Jan Konopacki, Jacek Jaworski
    Academic press:
    Plos One (rok: 2013, tom: 8, strony: e64455), Wydawca: PLOS
    Status:
    Published
  6. Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase
    Authors:
    Malik AR, Liszewska E, Skalecka A, Urbanska M, Iyer AM, Swiech LJ, Perycz M, Parobczak K, Pietruszka P, Zarebska MM, Macias M, Kotulska K, Borkowska J, Grajkowska W, Tyburczy ME, Jozwiak S, Kwiatkowski DJ, Aronica E, Jaworski J.
    Academic press:
    Acta Neuropathol Commun (rok: 2015, tom: 0,158333333333333, strony: 45304), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s40478-015-0225-z - link to the publication
  1. Spatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatment.
    Authors:
    Macias M. , Błażejczyk M., Kaźmierska P. , Caban B. , Skalecka A. , Tarkowski B., Konopacki J. , Jaworski J.
    Conference:
    11th International Congress of Polish Neuroscience Society (rok: 2013, ), Wydawca: Acta Neurobiologiae Experimentalis
    Data:
    konferencja 15-17.09.2013
    Status:
    Published