Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Monoclonal recombinant antibodies for the characterisation of important parasite molecules.

2012/05/B/NZ6/00777

Keywords:

monoclonal antibodies phage display libraries Fasciola hepatica

Descriptors:

  • NZ6_6: Parasitology
  • NZ6_3: Animal immunology
  • NZ6_8: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Parazytologii im. Witolda Stefańskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Luke Norbury 

Number of co-investigators in the project: 4

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 410 800 PLN

Project start date (Y-m-d): 2013-02-21

Project end date (Y-m-d): 2016-08-20

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zamarażarka laboratoryjna do głębokiego chłodzenia. (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Construction of a novel phage display antibody library against Fasciola hepatica, and generation of a single-chain variable fragment specific for F. hepatica cathepsin L1
    Authors:
    Luke J. Norbury, Katarzyna Basałaj, Piotr Baska, Alicja Kalinowska, Anna Zawistowska-Deniziak, Huan Yong Yap, Przemysław Wilkowski, Agnieszka Wesołowska, and Halina Wędrychowicz
    Academic press:
    Experimental Parasitology (rok: 2019, tom: 198, strony: 87-94), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.exppara.2019.02.001 - link to the publication
  2. Generation of a single-chain variable fragment phage display antibody library from naïve mice panned against Fasciola hepatica antigens
    Authors:
    Luke J. Norbury, Katarzyna Basałaj, Piotr Bąska, Anna Zawistowska-Deniziak, Alicja Kalinowska, Przemysław Wilkowski, Agnieszka Wesołowska, and Halina Wędrychowicz
    Academic press:
    Experimental Parasitology , Wydawca: Elsevier
    Status:
    Submitted