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Information on the principal investigator and host institution

Information of the project and the call

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Characterisation of the mechanism regulating expression of human HSPA2 gene in selected somatic cells.

2012/05/N/NZ1/00022

Keywords:

HSPA2 keratinocytes hypoxia NF-kappaB

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_5: Genetic engineering

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Habryka 

Number of co-investigators in the project: 2

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2013-03-21

Project end date (Y-m-d): 2015-03-20

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. Cell type-dependent modulation of the gene encoding heat shock protein HSPA2 by hypoxia-inducible factor HIF-1: Down-regulation in keratinocytes and up-regulation in HeLa cells.
    Authors:
    Anna Habryka; Agnieszka Gogler-Piglowska, Damian Sojka, Mariusz Kryj, Zdzislaw Krawczyk, Dorota Scieglinska
    Academic press:
    Biochemica et Biophysica Acta (rok: 2015, tom: 1849(9), strony: 1155-1169), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbagrm.2015.07.004 - link to the publication
  1. Dual role of HIF-1 in regulation of HSPA2 gene in cancer and normal cells
    Authors:
    Habryka A., Gogler – Pigłowska A., Kryj M., Sojka D., Krawczyk Z., Klyszcz K., Ścieglińska D.
    Conference:
    XVIII Gliwickie Spotkania Naukowe (rok: 2014, ), Wydawca: -
    Data:
    konferencja 21-22 listopad
    Status:
    Published
    DOI:
    link to the publication
  2. An intriguing role of HIF1alpha in regulation of HSPA2 in keratinocytes.
    Authors:
    Habryka A., Gogler-Pigłowska A., Kryj M., Krawczyk Z., Klarzyńska K., Ścieglińska D.
    Conference:
    XVII Gliwickie Spotkania Naukowe (rok: 2013, ), Wydawca: -
    Data:
    konferencja 15-16.11.
    Status:
    Published
  3. Role of hypoxia and Hypoxia Inducible factor 1alpha (HIF-1alpha) in regulation of the HSPA2 gene expression in human keratinocytes
    Authors:
    Habryka A., Gogler – Pigłowska A., Kryj M., Sojka D., Krawczyk Z., Ścieglińska D
    Conference:
    EACR-23: From basic science to personalised cancer treatment (rok: 2014, ), Wydawca: European Journal of Cancer
    Data:
    konferencja 5-8 lipca
    Status:
    Published
    DOI:
    link to the publication

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