Characterisation of the mechanism regulating expression of human HSPA2 gene in selected somatic cells.

2012/05/N/NZ1/00022

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ1_5: Inżynieria genetyczna

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Voivodeship: śląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Anna Julia Habryka

Number of co-investigators in the project: 2

Call

PRELUDIUM 3 – announced on 2012-03-15

Amount awarded
100 000 PLN
Project start date
2013-03-21
Project end date
2015-03-20
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (1)

  1. Cell type-dependent modulation of the gene encoding heat shock protein HSPA2 by hypoxia-inducible factor HIF-1: Down-regulation in keratinocytes and up-regulation in HeLa cells.

    Authors:
    Anna Habryka; Agnieszka Gogler-Piglowska, Damian Sojka, Mariusz Kryj, Zdzislaw Krawczyk, Dorota Scieglinska
    Academic press:
    Biochemica et Biophysica Acta (year: 2015, volume: 1849(9), pages: 1155-1169), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbagrm.2015.07.004 – link to the publication

Articles in post-conference publications (3)

  1. An intriguing role of HIF1alpha in regulation of HSPA2 in keratinocytes.

    Authors:
    Habryka A., Gogler-Pigłowska A., Kryj M., Krawczyk Z., Klarzyńska K., Ścieglińska D.
    Conference:
    XVII Gliwickie Spotkania Naukowe (year: 2013, pages: 143), Publisher: -
    Date:
    conference 15-16.11.
    Status:
    Published
  2. Dual role of HIF-1 in regulation of HSPA2 gene in cancer and normal cells

    Authors:
    Habryka A., Gogler – Pigłowska A., Kryj M., Sojka D., Krawczyk Z., Klyszcz K., Ścieglińska D.
    Conference:
    XVIII Gliwickie Spotkania Naukowe (year: 2014, pages: 79), Publisher: -
    Date:
    conference 21-22 listopad
    Status:
    Published
    DOI:
    link to the publication
  3. Role of hypoxia and Hypoxia Inducible factor 1alpha (HIF-1alpha) in regulation of the HSPA2 gene expression in human keratinocytes

    Authors:
    Habryka A., Gogler – Pigłowska A., Kryj M., Sojka D., Krawczyk Z., Ścieglińska D
    Conference:
    EACR-23: From basic science to personalised cancer treatment (year: 2014, pages: 50(1) S126), Publisher: European Journal of Cancer
    Date:
    conference 5-8 lipca
    Status:
    Published
    DOI:
    link to the publication

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