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The role of AnxA2-S100A10 complex in the initiation of mineralization by human osteoblast-like cells

2012/05/N/NZ3/00330

Keywords:

annexin A2 S100 proteins matrix vesicle mineralization osteoblasts

Descriptors:

  • NZ3_7: Signal transduction
  • NZ3_1: Cell biology
  • NZ5_7: Human disease treatment

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Anna Ćmoch 

Number of co-investigators in the project: 2

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2013-03-06

Project end date (Y-m-d): 2015-03-05

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (6)
  1. Biogenesis of invadopodia and their cellular functions
    Authors:
    Cmoch A., Groves P., Pikula S.
    Academic press:
    Postepy Biochemii (rok: 2014, tom: 60, strony: 62-68), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Stimulators of mineralization limit the invasive phenotype of human osteosarcoma cells by a mechanism involving impaired invadopodia formation
    Authors:
    Cmoch A., Podszywalow-Bartnicka P., Palczewska M., Piwocka K., Groves P., Pikula S.
    Academic press:
    Plos One (rok: 2014, tom: 9, strony: e109938), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pone.0109938 - link to the publication
  1. AnxA2 secreted by osteosarcoma cells may affect their migration and invasiveness but not mineralization
    Authors:
    Cmoch, A., Podszywalow-Bartnicka, P., Palczewska, M., Piwocka, K., Groves, P., Pikula, S.
    Conference:
    Do Science! Opening of the Academic Year 2013/2014 at Biocentrum Ochota w Warszawie, Polska (rok: 2013, ), Wydawca: Nie dotyczy
    Data:
    konferencja 25.10.2013
    Status:
    Published
    DOI:
    link to the publication
  2. The effect of AnxA2 on expansion of human osteosarcoma cells in vitro
    Authors:
    Cmoch, A., Podszywalow-Bartnicka, P., Palczewska, M., Piwocka, K., Groves, P., Pikula, S.
    Conference:
    48th Meeting of the Polish Biochemical Society w Toruniu, Polska (rok: 2013, ), Wydawca: Acta Biochimica Polonica (Polskie Towarzystwo Biochemiczne)
    Data:
    konferencja 2-5.09.2013
    Status:
    Published
    DOI:
    link to the publication
  3. The role of AnxA2-S100A10 complex in intracellular translocation of TRPV5/6 channels in osteoblast-like cells undergoing mineralization
    Authors:
    Cmoch A, Groves P, Pikula S
    Conference:
    Congress BIO 2014 (rok: 2014, ), Wydawca: Acta Biochimica Polonica (Polskie Towarzystwo Biochemiczne)
    Data:
    konferencja 09-12.09.
    Status:
    Published
    DOI:
    link to the publication
  4. The effect of exogenous AnxA2 on expansion and mineralization of human osteosarcoma (OS) cells in vitro
    Authors:
    Cmoch, A., Podszywalow-Bartnicka, P., Palczewska, M., Piwocka, K., Groves, P., Pikula, S.
    Conference:
    1st Nencki Institute PhD Student Conference International PhD Program in Neurobiology" w Warszawie, Polska (rok: 2013, ), Wydawca: Instytut Biologii Doświadczalnej PAN
    Data:
    konferencja 16-18.10.2013
    Status:
    Published
  5. Effect of exogenous annexin A2 on proliferation and mineralization of human osteosarcoma cells
    Authors:
    Cmoch, A., Palczewska, M., Podszywalow-Bartnicka, P., Piwocka, K., Groves, P., Pikula, S.
    Conference:
    Federation of European Biochemical Societies CONGRESS 2013 Mechanisms in Biology" in St.Petersburg, Russia (rok: 2013, ), Wydawca: FEBS Journal (WILEY-BLACKWELL)
    Data:
    konferencja 06-11.07.2013
    Status:
    Published
    DOI:
    link to the publication
  6. Invasiveness of human osteosarcoma 143B cells is significantly decreased in the presence of stimulators of mineralization
    Authors:
    Cmoch A, Podszywalow-Bartnicka P, Palczewska M, Piwocka K, Groves P, Pikula S
    Conference:
    ESF-EMBO Cell Polarity and Membrane Trafficking (rok: 2014, ), Wydawca: nie dotyczy
    Data:
    konferencja 10-15.05
    Status:
    Published

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