Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Analysis of metabolic profiles in urine in urinary bladder cancer

2012/05/B/NZ7/03293

Keywords:

metabolomics biomarkers urinary bladder cancer CE-LIF-TOF LC-LIF-TOF LC-MS/MS urine

Descriptors:

  • NZ2_4: Metabolomics

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Michał Markuszewski 

Number of co-investigators in the project: 7

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 873 571 PLN

Project start date (Y-m-d): 2013-02-13

Project end date (Y-m-d): 2016-08-12

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Elektroforeza kapilarna sprzężona z detektorem laserowo wzbudzanej fluorescencji (CE-LIF) (467 971 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Determination of pterins in urine by HPLC with UV and fluoroscent detection using different types of chromatographic stationary phases (HILIC, RP C8, RP C18)
    Authors:
    Kośliński P., Jarzemski P., Markuszewski M.J., Kaliszan R.
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2014, tom: 91, strony: 37-45), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pba.2013.12.012 - link to the publication
  2. Metabolomic heterogeneity of urogenital tract cancers analyzed by complementary chromatographic techniques coupled with mass spectrometry
    Authors:
    Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Renata Bujak, Marcin Markuszewski, Marek Roslan, Roman Kaliszan, Michał Jan Markuszewski
    Academic press:
    Current Medicinal Chemistry (rok: 2018, tom: 25, strony: 45307), Wydawca: BENTHAM SCIENCE PUBL LTD
    Status:
    Published
    DOI:
    10.2174/0929867324666171006150326. - link to the publication
  3. Analysis of urinary nucleosides as potential cancer markers determined using LC--MS technique
    Authors:
    Struck-Lewicka W., Kaliszan R., Markuszewski M.J.
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2014, tom: 101, strony: 50-57), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2014.04.022 - link to the publication
  4. Statistical-based approach in potential diagnostic application of urinary nucleosides in urogenital tract cancer
    Authors:
    Emilia Daghir-Wojtkowiak, Wiktoria Struck-Lewicka, Malgorzata Waszczuk-Jankowska, Marcin Markuszewski, Roman Kaliszan, Michal Jan Markuszewski
    Academic press:
    Biomarkers in Medicine (rok: 2015, tom: 9, strony: 577-595), Wydawca: Future Medicine Ltd
    Status:
    Published
    DOI:
    10.2217/bmm.15.20 - link to the publication
  5. Metabolomics for laboratory diagnostics
    Authors:
    Renata Bujak, Wiktoria Struck-Lewicka, Michał J. Markuszewski, Roman Kaliszan
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2015, tom: 113, strony: 108-120), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2014.12.017 - link to the publication
  6. The metabolic profiles of pterin compounds as potential biomarkersof bladder cancer—Integration of analytical-based approach withbiostatistical methodology
    Authors:
    Piotr Kośliński, Emilia Daghir-Wojtkowiab, Paulina Szatkowska-Wanda, Marcin Markuszewski, Michał J. Markuszewski
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2016, tom: 127, strony: 256–262), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2016.02.038 - link to the publication

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