Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Studies on the role of selected scavenger receptors in the biology of macrophages and dendritic cells.

2012/05/B/NZ6/00813

Keywords:

scavenger receptors pattern recognition receptors endocytosis MARCO CD36 CD204 cytokines oxidative burst

Descriptors:

  • NZ6_1: Adaptive and innate immunity
  • NZ3_7: Signal transduction
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Szczepan Józefowski 

Number of co-investigators in the project: 6

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 653 968 PLN

Project start date (Y-m-d): 2013-01-28

Project end date (Y-m-d): 2016-01-27

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Czytnik płytek do pomiaru fluorescencji i absorbancji (190 000 PLN)
  2. Aparat do nukleofekcji (90 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. CD36 Differently Regulates Macrophage Responses to Smooth and Rough Lipopolysaccharide.
    Authors:
    Biedroń R, Peruń A, Józefowski S.
    Academic press:
    Plos One (rok: 2016, tom: 11, strony: e0153558), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0153558 - link to the publication
  2. The class A scavenger receptor SR-A/CD204 and the class B scavenger receptor CD36 regulate immune functions of macrophages differently
    Authors:
    Józefowski S, Biedron R, Sróttek M, Chadzinska M, Marcinkiewicz J.
    Academic press:
    Innate Immunity (rok: 2014, tom: 20, strony: 826-847), Wydawca: SAGE journals
    Status:
    Published
    DOI:
    10.1177/1753425913510960 - link to the publication
  3. The danger model: questioning an unconvincing theory.
    Authors:
    Józefowski S
    Academic press:
    Immunology & Cell Biology (rok: 2016, tom: 94, strony: 164-168), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/icb.2015.68 - link to the publication
  4. Phagocytosis of live versus killed or fluorescently labeled bacteria by macrophages differ in both magnitude and receptor specificity.
    Authors:
    Peruń A, Biedroń R, Konopiński MK, Białecka A, Marcinkiewicz J, Józefowski S.
    Academic press:
    Immunology and Cell Biology (rok: 2017, tom: 95, strony: 424-435), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/icb.2016.112 - link to the publication