Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Conversion of natural disaccharides into uronic acid derivatives and their application to the synthesis of steroid-containing glycosides and modern anticoagulant agents

2012/05/B/ST5/00275

Keywords:

carbohydrates uronic acids glycosylation protecting groups synthesis heparin saponin

Descriptors:

  • ST5_23:
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Młynarski 

Number of co-investigators in the project: 5

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 799 998 PLN

Project start date (Y-m-d): 2013-02-04

Project end date (Y-m-d): 2016-10-03

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. blok reaktorowy z mieszadłem (40 000 PLN)
  2. lodówka.
  3. półautomatyczny aparat chromatografii flash (200 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Application of 2-Substituted Benzyl Groups in Stereoselective Glycosylation
    Authors:
    Szymon Buda, Mirosław Nawój, Patrycja Gołębiowska, Karol Dyduch, Andrzej Michalak, Jacek Mlynarski
    Academic press:
    The Journal Of Organic Chemistry (rok: 2015, tom: 80, strony: 770-780), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/jo502186f - link to the publication
  2. Synthesis of l-Pyranosides by Hydroboration of Hex-5-enopyranosides Revisited
    Authors:
    Grzegorz Łopatkiewicz, Jacek Mlynarski
    Academic press:
    The Journal of Organic Chemistry (rok: 2016, tom: 81, strony: 7545–7556), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.joc.6b01243 - link to the publication
  3. Application of the 2-Nitrobenzyl Group in Glycosylation Reactions: A Valuable Example of an Armig Participating Group
    Authors:
    Szymon Buda, Patrycja Gołębiowska, Jacek Mlynarski
    Academic press:
    European Journal of Organic Chemistry (rok: 2013, tom: -, strony: 3988-3991), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/ejoc.201300123 - link to the publication
  4. Synthesis and Application of Uronic Acids
    Authors:
    Marcin Nowogródzki, Jacek Mlynarski
    Academic press:
    Current Organic Chemistry (rok: 2014, tom: 18, strony: 1913-1934), Wydawca: Bentham Science
    Status:
    Published
    DOI:
    10.2174/1385272819666140527232825 - link to the publication