Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effects of inflammation on the brain susceptibility to seizures. Postinflammatory changes in the nervous tissue as determinants of epileptogenesis

2012/05/B/NZ4/02406

Keywords:

generalized inflammation brain. development epilepsy seizure neurodegeneration

Descriptors:

  • NZ4_4: Pathophysiology
  • NZ4_5: Anatomical pathology
  • NZ4_9: Systems neurobiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Zuzanna Setkowicz 

Number of co-investigators in the project: 5

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 400 040 PLN

Project start date (Y-m-d): 2013-03-06

Project end date (Y-m-d): 2016-12-05

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Transmitery do zdalnej rejestracji EEG (16 szt.) (60 000 PLN)
  2. Moduł do analizy białek.
  3. Program Neuroscore do analizy danych z EEG (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Volumetric response of the adult brain to seizures depends on the developmental stage when systemic inflammation was induced
    Authors:
    Krzysztof Janeczko,Emilia Kosonowska ,Artur Kiepura ,Wladyslaw Weglarz ,Zuzanna Setkowicz
    Academic press:
    Epilepsy and Behavior (rok: 2018, tom: 78, strony: 280-287), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.yebeh.2017.09.009. - link to the publication
  2. Inflammation in the developing rat modulates astroglial reactivity to seizures in the mature brain
    Authors:
    Zuzanna Setkowicz , Emilia Kosonowska, Krzysztof Janeczko
    Academic press:
    Journal of Anatomy (rok: 2017, tom: 23, strony: 23-33), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/joa.12636 - link to the publication
  3. Inflammation induced at different developmental stages affects differently the range of microglial reactivity and the course of seizures evoked in the adult rat.
    Authors:
    Kosonowska E, Janeczko K, Setkowicz Z.
    Academic press:
    Epilepsy and Behavior (rok: 2015, tom: 49, strony: 66-70), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.yebeh.2015.04.063 - link to the publication

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