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Helicobacter pylori Dsb (disulfide bond) proteins - analysis of the relations between sequence, structure and function of HP0231 and HP0377

2012/05/B/NZ1/00039

Keywords

Descriptors

  • NZ1_10: Biologia drobnoustrojów
  • NZ1_1: Biologia molekularna
  • NZ1_5: Inżynieria genetyczna

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Warszawski, Wydział Biologii

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Elżbieta Katarzyna Jagusztyn-Krynicka

Number of co-investigators in the project: 6

Call

OPUS 3 – announced on 2012-03-15

Amount awarded
500 000 PLN
Project start date
2013-02-12
Project end date
2016-02-11
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. AKTA purifing system - firma GE Healthcare Life Sciences. Cost: 80 000 PLN
  2. Aparat Trans blot Turbo - uzupełnienie aparatury do oczyszczania białek , opłata części kosztów.

Information in the final report

Publication in academic press/journals (8)

  1. Functional and evolutionary analyses of Helicobacter pylori HP0231( DsbK) protein characterized by a highly diverged dimerization domain and strong oxidative and chaperon activities

    Authors:
    Katarzyna M. Bocian-Ostrzycka, Anna M. Łasica, Stanislaw Dunin-Horkawicz, Magdalena Grzeszczuk, Karolina Drabik, Aneta M. Dobosz, Renata Godlewska, Elzbieta Nowak,Jean-Francois Colletb, E. Katarzyna Jagusztyn-Krynicka
    Academic press:
    Frontiers in Microbiology (year: 2016, volume: 6, pages: 1065), Publisher: Frontiers is a community-rooted, open-access academic publisher
    Status:
    Published
    DOI:
    10.3389/fmicb.2015.01065 – link to the publication

  2. Diversity of the Epsilonproteobacteria Dsb (disulfide bond) systems

    Authors:
    Katarzyna Marta Bocian-Ostrzycka, Magdalena Joanna Grzeszczuk, Lukasz Dziewit and Elzbieta Katarzyna Jagusztyn-Krynicka
    Academic press:
    Frontiers in Microbiology, (year: 2015, volume: 6, pages: 570), Publisher: Frontiers is a community-rooted, open-access academic publisher
    Status:
    Published
    DOI:
    10.3389/fmicb.2015.00570 – link to the publication

  3. Engineering of Helicobacter pylori dimeric oxidoreductase DsbK (HP0231) – the role of catalytic motifs and the N-terminal dimerization domain

    Authors:
    Katarzyna M. Bocian-Ostrzycka, Magdalena J. Grzeszczuk, Anna M. Banaś, Katarzyna Jastrząb, Karolina Pisarczyk, Anna M. Kolarzyk, Anna M. Łasica, Jean-François Collet, Elżbieta K. Jagusztyn-Krynicka
    Academic press:
    Frontiers in Microbiology (year: 2016, volume: 7, pages: 1158), Publisher: Frontiers is a community-rooted, open-access academic publisher
    Status:
    Published
    DOI:
    10.3389/fmicb.2016.01158 – link to the publication

  4. Helicobacter pylori HP0231 influences bacterial virulence and is essential for gastric colonization

    Authors:
    Yu Zhong, Florian Anderl, Tobias Kruse, Franziska Schindele, Elżbieta Katarzyna Jagusztyn-Krynicka, Wolfgang Fische, Markus Gerhard and Raquel Mejías-Luque
    Academic press:
    PLos ONE (year: 2016, volume: 11, pages: 46035), Publisher: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0154643. – link to the publication

  5. Proces biogenezy cytochromów c w komórkach bakteryjnych - rola białek Dsb (disulfide bond)

    Authors:
    Paula Roszczenko, Magdalena Grzeszczuk, Elżbieta Katarzyna Jagusztyn-Krynicka
    Academic press:
    Postępy Mikrobiologii (year: 2014, volume: 53, pages: 318 - 327), Publisher: PTM
    Status:
    Published

  6. Detection of Protein Oxidative Activity Using Reduced RNase A

    Authors:
    Magdalena Grzeszczuk, Katarzyna Bocian-Ostrzycka, Anna Lasica and E. Katarzyna Jagusztyn-Krynicka
    Academic press:
    Bio-protocol (year: 2016, volume: 6, pages: iss 6), Publisher: e-journal załozony w 2011 przez naukowców ze Stanford Uniwersytetu
    Status:
    Published
    DOI:
    link to the publication

  7. Helicobacter pylori HP0377, a member of the Dsb family, is an untypical multifunctional CcmG that cooperates with dimeric thioldisulfide oxidase HP0231

    Authors:
    Paula Roszczenko, Magdalena Grzeszczuk, Patrycja Kobierecka, Ewa Wywial, Paweł Urbanowicz, Piotr Wincek, E. Katarzyna Jagusztyn- Krynicka
    Academic press:
    BMC Microbiol. (year: 2015, volume: 15, pages: 135-153), Publisher: Bio MedCentral
    Status:
    Published
    DOI:
    10.1186/s12866-015-0471-z – link to the publication

  8. Różnorodność szlaków utleniania Dsb (disulfide bond) w świecie mi,roorganizmów

    Authors:
    Aneta Dobosz, Katarzyna Bocian-Ostrzycka i Elżbieta Katarzyna Jagusztyn-Krynicka
    Academic press:
    Postępy Mikrobiologii (year: 2015, volume: 1, pages: 21-32), Publisher: PTM
    Status:
    Published

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