Projects funded by the NCN
Identification of amino acid residues located in positions P7 and P8 of model inhibitor of proprotein convertases that determine increasing its specificity toward PACE4
2012/05/N/ST5/01080
Keywords:
proprotein convertases inhibitors synthesis of peptides 4-amidinobenzylamine
Descriptors:
- ST5_23:
- ST5_16:
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Uniwersytet Gdański, Wydział Chemii
woj. pomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 3 - announced on 2012-03-15
Amount awarded: 50 000 PLN
Project start date (Y-m-d): 2013-02-13
Project end date (Y-m-d): 2014-02-12
Project duration:: 12 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- hybrydowa pompa chemoodporna (RC 6, Vacuubrand) (15 000 PLN)
Information in the final report
- Publication in academic press/journals (1)
- Articles in post-conference publications (1)
- Book publications / chapters in book publications (1)
- Positional scanning identifies the molecular determinants of a high affinity Multi-Leucine inhibitor for furin and PACE4Authors:I. Małuch, C. Levesque, A. Kwiatkowska, F. Couture, K. Ly, R. Desjardins, W.A. Neugebauer, A. Prahl, R. DayAcademic press:Journal of Medicinal Chemistry (rok: 2017, tom: brak, strony: xxx-xxx), Wydawca: ACS PublicationsStatus:PublishedDOI:10.1021/acs.jmedchem.6b01499 - link to the publication
- "Chemical synthesis and analysis of short peptides containing modified arginine residues"Authors:I. Małuch, M. Lewandowska, T. Łepek, B. Lammek, A. PrahlConference:23rd American Peptide Symposium and 6th International Peptide Symposium (rok: 2013, ), Wydawca: American Peptide Society/ editor: Michal LeblData:konferencja 22-27 czerwca 2013, HawajeStatus:Published
- "Konwertazy probiałkowe oraz ich inhibitory"Authors:I. Małuch, A. PrahlBook:"Na pograniczu chemii i biologii" (rok: 2013, tom: XXXI, strony: 279-287), Wydawca: Wydawnictwo Naukowe Uniwersytetu im. Adama MickiewiczaStatus:Published