Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Neuronal mechanisms of peptidergic regulation of stress inducted overeating

2012/05/D/NZ4/02984

Keywords:

Relaxin-3 stress food intake electrophysiology behavioural studies

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ3_7: Signal transduction

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Błasiak 

Number of co-investigators in the project: 4

Call: SONATA 3 - announced on 2012-03-15

Amount awarded: 485 308 PLN

Project start date (Y-m-d): 2013-02-14

Project end date (Y-m-d): 2016-02-13

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputer stacjonarny (3 497 PLN)
  2. Komputer stacjonarny z monitorem.
  3. System monitoringu dla fizjologicznego i behawioralnego fenotypowania zwierząt laboratoryjnych (8 szt.) (190 000 PLN)
  4. Zestaw do zadawania kontrolowanego szoku elektrycznego dla szczurów (4 szt.) (32 500 PLN)
  5. Podstaw klatek bytowych wraz z komplementarnymi pokrywami i butelkami (8 545 PLN)
  6. Podstawy klatek do zestawu PhenoMaster.
  7. Zestaw do unieruchamiania zwierząt.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (10)
  1. Distribution, physiology and pharmacology of relaxin-3/RXFP3 systems in brain
    Authors:
    Sherie Ma, Craig M. Smith, Anna Blasiak, Andrew L. Gundlach
    Academic press:
    British Journal of Pharmacology (rok: 2017, tom: 10, strony: 1034-1048), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/bph.13659 - link to the publication
  2. Excitatory orexinergic innervation of rat nucleus incertus - Implications for ascending arousal, motivation and feeding control
    Authors:
    Anna Blasiak, Marcin Siwiec, Agnieszka Grabowiecka, Tomasz Blasiak, Anna Czerw, Ewa Blasiak, Alan Kania, Zenon Rajfur, Marian H. Lewandowski, Andrew L. Gundlach
    Academic press:
    Neuropharmacology (rok: 2015, tom: 99, strony: 432-447), Wydawca: PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
    Status:
    Published
    DOI:
    10.1016/j.neuropharm.2015.08.014 - link to the publication
  3. Inhibition of oxytocin and vasopressin neuron activity in rat hypothalamic paraventricular nucleus by relaxin-3-RXFP3 signalling
    Authors:
    Alan Kania, Anna Guguła, Agnieszka Grabowiecka, Camila Avila, Tomasz Blasiak, Zenon Rajfur, Marian H. Lewandowski, Grzegorz Hess, Elena Timofeeva, Andrew L. Gundlach, Anna Blasiak
    Academic press:
    The Journal of Physiology (LONDON) (rok: 2017, tom: 11, strony: 3425-3447), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1113/JP273787 - link to the publication
  4. Nucleus incertus Orexin2 receptors mediate alcohol seeking in rats
    Authors:
    Hanna E. Kastman, Anna Blasiak, Leigh Walker, Marcin Siwiec, Elena V. Krstew, Andrew L. Gundlach, Andrew J. Lawrence
    Academic press:
    Neuropharmacology (rok: 2016, tom: 110, strony: 82-91), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuropharm.2016.07.006 - link to the publication
  5. Relaksyna-3 i receptory rodziny peptydów relaksynowych – od struktury po funkcje nowo odkrytego układu mózgowia ssaków
    Authors:
    Alan Kania, Marian H. Lewandowski, Anna Błasiak
    Academic press:
    Postepy Higieny i Medycyny Doświadczalnej (rok: 2014, tom: 68, strony: 851-864), Wydawca: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/17322693.1110163 - link to the publication
  1. Ghrelin meets the nucleus incertus - the behavioural effect in the rat
    Authors:
    Agnieszka Grabowiecka, Marcin Siwiec, Sherie Ma, Hannah Kastman, Grzegorz Hess, Anna Blasiak, Andrew Gundlach
    Conference:
    NEURONUS 2014 IBRO & IRUN Neuroscience Forum (rok: 2014, ), Wydawca: STUDENT NEUROSCIENCE SOCIETY ' NEURONUS '
    Data:
    konferencja 25-27.04
    Status:
    Published
  2. Immunohistochemical identification of orexin A and B in nucleus incertus of the rat
    Authors:
    Anna Czerw, Andrew Gundlach, Marian H. Lewandowski, Anna Blasiak
    Conference:
    NEURONUS 2014 IBRO & IRUN Neuroscience Forum (rok: 2014, ), Wydawca: STUDENT NEUROSCIENCE SOCIETY ' NEURONUS '
    Data:
    konferencja 25-27.04
    Status:
    Published
  3. Interactions of relaxin-3 and other neuropeptide systems regulating arousal and feeding in rats
    Authors:
    Anna Blasiak, Alan Kania, Agnieszka Grabowiecka, Anna Czerw, Marcin Siwiec, Tomasz Blasiak, Andrew L. Gundlach
    Conference:
    7th International Conference on Relaxin and Related Peptides (rok: 2015, ), Wydawca: International Conference on Relaxin and Related Peptides
    Data:
    konferencja 20-24 wrzesień
    Status:
    Published
  4. Relaxin - 3/RXFP3 networks in food int ake and stress responses - neural mechanisms underlying behavioural effects
    Authors:
    Blasiak, Anna; Kania, Alan; Lewandowski, Marian H.; Gundlach, Andrew L.
    Conference:
    24th Annual Meeting of the International Behavioral Neuroscience Society (rok: 2015, ), Wydawca: International Behavioral Neuroscience Society
    Data:
    konferencja 2-7 lipiec
    Status:
    Published
  5. Relaxin - 3/RXFP3 signalling in the paraventric ular nucleus of hypothalamus (PVN) of rats – insights into the sexual differences in stress - related food intake
    Authors:
    Alan Kania, Gundlach A.L., Lewandowski M.H., Hess G., Blasiak A.
    Conference:
    8th edition of the NEURONUS IBRO & IRUN Neuroscience Forum (rok: 2015, ), Wydawca: NEURONUS IBRO & IRUN Neuroscience Forum
    Data:
    konferencja 17-19 kwiecień
    Status:
    Published
  6. The impact of ghrelin on nucleus incertus activity in vitro: possible causal link between two feeding control circuits
    Authors:
    Marcin Siwiec, Agnieszka Grabowiecka, Grzegorz Hess, Andrew L. Gundlach, Anna Blasiak
    Conference:
    NEURONUS 2014 IBRO & IRUN Neuroscience Forum (rok: 2014, ), Wydawca: STUDENT NEUROSCIENCE SOCIETY ' NEURONUS '
    Data:
    konferencja 25-27.04
    Status:
    Published
  7. Neural interfaces of stress and feeding: Electrophysiological studies of relaxin-3/RXFP3 signalling in the hypothalamic paraventricular nucleus (PVN) of the rat
    Authors:
    Alan Kania, Marian H. Lewandowski, Grzegorz Hess, M. Akhter Hossain, Andrew L. Gundlach, Anna Blasiak
    Conference:
    9th IBRO World Congress of Neuroscience (rok: 2015, ), Wydawca: The International Brain Research Organization (IBRO)
    Data:
    konferencja 7-11 lipiec
    Status:
    Published
  8. RELAXIN - 3 IN THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS (PVN) OF RAT. ELECTROPHYSIOLOGICAL APPROACH TO UNDERSTAND THE SEX - DEPENDENT RELATIONS BETWEEN STRESS AND FEEDING
    Authors:
    Alan Kania, Marian h. Lewandowski, Grzegorz Hess, m. Akhter Hossain, Andrew L. Gundlach, Anna Błasiak
    Conference:
    12th International Congress of the Polish Neuroscience Society (rok: 2015, ), Wydawca: Polish Neuroscience Society (PNS)
    Data:
    konferencja 6-8 wrzesień
    Status:
    Published
  9. Relaxin-3/RXFP3 networks in food intake and stress responses.
    Authors:
    Blasiak A.
    Conference:
    Progress In biomedicine & neuromedicine Humboldt-Kolleg – workshop (rok: 2015, ), Wydawca: Marian Jaskuła
    Data:
    konferencja 21-23 Czerwiec
    Status:
    Published
  10. 'Direct action of relaxin-3 receptor (RXFP3) agonist on hypothalamic paraventricular nucleus (PVN) neurons in the rat - in vitro patch clamp study.', NEURONUS
    Authors:
    Kania A., Gundlach A.L., Lewandowski M.H., Blasiak A.
    Conference:
    NEURONUS 2014 IBRO & IRUN Neuroscience Forum (rok: 2014, ), Wydawca: STUDENT NEUROSCIENCE SOCIETY ' NEURONUS '
    Data:
    konferencja 25-27.04
    Status:
    Published