Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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MicroRNAs in tumor-derived exosomes: possible contribution to cancer immune suppression

2012/05/B/NZ2/00574

Keywords:

exosome microRNA cancer immunosuppression dendritic cells

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Centrum Badań Molekularnych i Makromolekularnych PAN

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Markus Düchler 

Number of co-investigators in the project: 6

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 698 494 PLN

Project start date (Y-m-d): 2013-03-12

Project end date (Y-m-d): 2016-03-11

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Aparat do RT-PCR w czasie rzeczywistym (qRT-PCR) (126 000 PLN)
  2. zestaw do dekontaminacji nadtlenkiem wodoru z generatorem (9 100 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Analysis of the miRNA Profiles of Melanoma Exosomes Derived Under Normoxic and Hypoxic Culture Conditions
    Authors:
    MICHAL WOZNIAK, LUKASZ PECZEK, LILIANA CZERNEK and MARKUS DÜCHLER
    Academic press:
    ANTICANCER RESEARCH (rok: 2017, tom: 37, strony: 6779-6789), Wydawca: International Institute of Anticancer Research (IIAR)
    Status:
    Published
    DOI:
    10.21873/anticanres.12138 - link to the publication
  2. MiRNA in melanoma-derived exosomes
    Authors:
    Gajos-Michniewicz A, Duechler M, Czyz M
    Academic press:
    Cancer Letters (rok: 2014, tom: 347, strony: 29-37), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.canlet.2014.02.004 - link to the publication
  3. Functions of Cancer-Derived Extracellular Vesicles in Immunosuppression
    Authors:
    Liliana Czernek, Markus Düchler
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2017, tom: 65 (4), strony: 311–323), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00005-016-0453-3 - link to the publication
  4. The Uptake of Extracellular Vesicles is Affected by the Differentiation Status of Myeloid Cells
    Authors:
    Czernek L, Chworos A, Duechler M
    Academic press:
    Scandinavian Journal of Immunology (rok: 2015, tom: 82(6), strony: 506-14), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1111/sji.12371 - link to the publication

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