Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Preparation and characterization of nanoapatites doped with rare earth ions and their biocomposites.

2012/05/E/ST5/03904

Keywords:

Nanomaterials bioactivity drug-delivery bio-imaging

Descriptors:

  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • ST5_3: Surface modification
  • ST4_3: Molecular architecture and structure

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Rafał Wiglusz 

Number of co-investigators in the project: 8

Call: SONATA BIS 1 - announced on 2012-03-15

Amount awarded: 1 319 000 PLN

Project start date (Y-m-d): 2013-01-30

Project end date (Y-m-d): 2019-03-29

Project duration:: 74 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (25)
  • Book publications / chapters in book publications (2)
  1. Co-expression of the aryl hydrocarbon receptor and estrogen receptor in the developing teeth of rat offspring after rat mothers' exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and the protective action of α-tocopherol and acetylsalicylic acid
    Authors:
    Maciej Dobrzyński, Piotr Kuropka, Anna Leśków, Katarzyna Herman, Małgorzata Tarnowska, Rafał J. Wiglusz
    Academic press:
    Advances in Clinical and Experimental Medicine (rok: 2019, tom: 28(7), strony: 45299), Wydawca: Wroclaw Medical University
    Status:
    Published
    DOI:
    10.17219/acem/99613 - link to the publication
  2. Influence of surface modifications of a nanostructured implant on osseointegration capacity – preliminary in vivo study
    Authors:
    Maciej Janeczek, Patrycja Szymczyk, Maciej Dobrzynski, Olga Parulska, Maria Szymonowicz, Piotr Kuropka, Zbigniew Rybak, Boguslawa Zywicka, Grzegorz Ziolkowski, Krzysztof Marycz, Aleksander Chroszcz, Aleksandra Skalec, Sara Targonska and Rafal J. Wiglusz
    Academic press:
    RSC Advances (rok: 2018, tom: 8, strony: 15533-15546), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8RA01625A - link to the publication
  3. Structural and spectroscopic properties of Yb3+-doped MgAl2O4 nanocrystalline spinel
    Authors:
    Rafael J Wiglusz, Georges Boulon, Yannick Guyot, Malgorzata Guzik, Dariusz Hreniak and Wiesław Stręk
    Academic press:
    Dalton Transactions (rok: 2014, tom: 43, strony: 7752-7759), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C3DT53644K - link to the publication
  4. Study of Surface Structure Changes for Selected Ceramics Used in the CAD/CAM System on the Degree of Microbial Colonization, In Vitro Tests
    Authors:
    Maciej Dobrzynski, Magdalena Pajaczkowska, Joanna Nowicka, Aleksander Jaworski, Piotr Kosior, Maria Szymonowicz, Piotr Kuropka, Zbigniew Rybak, Zdzislaw A. Bogucki, Jaroslaw Filipiak, Sara Targonska, Aneta Ciupa-Litwa, Anna Han, Rafal J. Wiglusz
    Academic press:
    BioMed Research International (rok: 2019, tom: 2019, strony: 9130806), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2019/9130806 - link to the publication
  5. Preferential site occupancy of Eu3+ ions in strontium hydroxyapatite nanocrystalline – Sr10(PO4)6(OH)2 – structural and spectroscopic characterisation
    Authors:
    Katarzyna Zawisza and Rafal J. Wiglusz
    Academic press:
    Dalton Transactions (rok: 2017, tom: 46, strony: 3265-3275), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C6DT04731A - link to the publication
  6. Influence of the grain sizes on Stokes and anti-Stokes fluorescence in the Yb3+ and Tb3+ ions co-doped nanocrystalline fluorapatite
    Authors:
    Paulina Sobierajska, Rafal J. Wiglusz
    Academic press:
    Journal of Alloys and Compounds (rok: 2019, tom: 785, strony: 808-818), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jallcom.2019.01.146 - link to the publication
  7. Li+ activated nanohydroxyapatite doped with Eu3+ ions enhances proliferative activity and viability of human stem progenitor cells of adipose tissue and olfactory ensheathing cells. Further perspective of nHAP:Li+, Eu3+ application in theranostics
    Authors:
    Krzysztof Marycz, Paulina Sobierajska, Agnieszka Smieszek, Monika Marędziak, Katarzyna Wiglusz, Rafał J. Wiglusz
    Academic press:
    Materials Science & Engineering C (rok: 2017, tom: 78, strony: 151-162), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2017.04.041 - link to the publication
  8. The influence of high doses of α-tocopherol on the content of selected trace elements in the liver of developing chicken embryos in experimentally induced 2,3,7,8-tetrachlorodibenzop- dioxin intoxication
    Authors:
    Piotr Kuropka, Maciej Dobrzynski, Malgorzata Tarnowska, Marzena Styczynska, Krzysztof Dudek, Anna Leskow, Rafal J. Wiglusz
    Academic press:
    Acta Biochimica Polonica (rok: 2019, tom: 66, strony: 223-228), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/abp.2018_2789 - link to the publication
  9. Forgotten and Resurrected Chernovite-(Y): YAsO4 Doped with Eu3+ Ions as a Potential Nanosized Luminophore
    Authors:
    Adam Strzep, Adam Watras, Katarzyna Zawisza, Philippe Boutinaud, and Rafal J. Wiglusz
    Academic press:
    Inorganic Chemistry (rok: 2017, tom: 56, strony: 10914 - 1092), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.inorgchem.7b01089 - link to the publication
  10. Modulating effect of selected pharmaceuticals on bone in female rats exposed to 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD)
    Authors:
    Maciej Dobrzynski, Celina Pezowicz, Magdalena Tomanik, Piotr Kuropka, Krzysztof Dudek, Katarzyna Fita, Marzena Styczynska, Rafal J. Wiglusz
    Academic press:
    RSC Advances (rok: 2018, tom: 8, strony: 27537-27545), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8RA03619E - link to the publication
  11. Multifunctional nanocrystalline calcium phosphates loaded with Tetracycline antibiotic combined with human adipose derived mesenchymal stromal stem cells (hASCs)
    Authors:
    K. Marycz, R. Pazik, K. Zawisza, K. Wiglusz, M. Maredziak, P. Sobierajska and R.J. Wiglusz
    Academic press:
    Materials Science & Engineering C (rok: 2016, tom: 69, strony: 17-26), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2016.06.051 - link to the publication
  12. New approach to modification of poly (L-lactic acid) with nanohydroxyapatite improving functionality of human adipose-derived stromal cells (hASCs) through increased viability and enhanced mitochondrial activity
    Authors:
    Agnieszka Smieszek, Krzysztof Marycz, Konrad Szustakiewicz, Bartłomiej Kryszak, Sara Targonska, Katarzyna Zawisza, Adam Watras, Rafal J. Wiglusz
    Academic press:
    Materials Science & Engineering C (rok: 2019, tom: 98, strony: 213–226), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2018.12.099 - link to the publication
  13. Preparation and antimicrobial activity of the porous hydroxyapatite nanoceramics
    Authors:
    Paulina Sobierajska, Agata Dorotkiewicz-Jach, Katarzyna Zawisza, Janina Okal, Tomasz Olszak, Zuzanna Drulis-Kawa, Rafal J. Wiglusz
    Academic press:
    Journal of Alloys and Compounds (rok: 2018, tom: 748, strony: 179 - 187), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jallcom.2018.03.162 - link to the publication
  14. Up-converting HAP@β-TCP nanocomposite activated with Er3+/Yb3+ ion-pairs for bio-related applications
    Authors:
    R. J. Wiglusz, B. Poźniak, K. Zawisza and R. Pazik
    Academic press:
    RSC Advances (rok: 2015, tom: 5, strony: 27610-27622), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C5RA00675A - link to the publication
  15. A new approach to spectroscopic and structural studies of the nano-sized silicate-substituted hydroxyapatite doped with Eu3+ ions
    Authors:
    S. Targonska, K. Szyszka, J. Rewak-Soroczynska, R.J. Wiglusz
    Academic press:
    Dalton Transactions (rok: 2019, tom: 48, strony: 8303-8316), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c9dt01025d - link to the publication
  16. Cytotoxicity Evaluation of High-Temperature Annealed Nanohydroxyapatite in Contact with Fibroblast Cells
    Authors:
    Maria Szymonowicz, Mariusz Korczynski, Maciej Dobrzynski , Katarzyna Zawisza, Marcin Mikulewicz, Ewa Karuga-Kuzniewska, Boguslawa Zywicka, Zbigniew Rybak and Rafal J.Wiglusz
    Academic press:
    Materials (rok: 2017, tom: 10, strony: 590 - 603), Wydawca: MDPI Publisher
    Status:
    Published
    DOI:
    10.3390/ma10060590 - link to the publication
  17. Influence of annealing temperature on the spectroscopic properties of hydroxyapatite analogues doped with Eu3+
    Authors:
    Katarzyna Zawisza, Adam Strzep and Rafal J. Wiglusz
    Academic press:
    New Journal of Chemistry (rok: 2017, tom: 41, strony: 9990 - 9999), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c7nj01380a - link to the publication
  18. Lithium ions (Li+) and nanohydroxyapatite (nHAp) doped with Li+ enhance expression of late osteogenic markers in adipose-derived stem cells. Potential theranostic application of nHAp doped with Li+ and co-doped with europium (III) and samarium (III) ions
    Authors:
    M. Alicka, P. Sobierajska, K. Kornicka, R.J. Wiglusz, K. Marycz
    Academic press:
    Materials Science & Engineering C (rok: 2019, tom: 99, strony: 1257–1273), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2019.02.073 - link to the publication
  19. Preparation and preliminary evaluation of bio-nanocomposites based on hydroxyapatites with antibacterial properties against anaerobic bacteria
    Authors:
    Katarzyna Zawisza, Paulina Sobierajska, Nicole Nowak, Anna Kedziora, Kamila Korzekwa, Blazej Pozniak, Marta Tikhomirov, Julia Miller, Lucyna Mrowczynska, Rafal J. Wiglusz
    Academic press:
    Materials Science & Engineering C (rok: 2020, tom: 106, strony: 110259), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2019.110295 - link to the publication
  20. Structural and Spectroscopic Characterization of Nd3+-Doped YVO4 Yttrium Orthovanadate Nanocrystallites
    Authors:
    R. J. Wiglusz, L. Marciniak , R. Pazik and W. Strek
    Academic press:
    Crystal Growth & Design (rok: 2014, tom: 14(11), strony: 5512-5520), Wydawca: American Chemical Society Publications
    Status:
    Published
    DOI:
    10.1021/cg500686h - link to the publication
  21. Structural modification of nanohydroxyapatite Ca10(PO4)6(OH)2 related to Eu3+ and Sr2+ ions doping and its spectroscopic and antimicrobial properties
    Authors:
    Katarzyna Szyszka, Justyna Rewak-Soroczynska, Agata Dorotkiewicz-Jach, Karolina Ledwa, Agata Piecuch, Michael Giersig, Zuzanna Drulis-Kawa, Rafal J. Wiglusz
    Academic press:
    Journal of Inorganic Biochemistry (rok: 2020, tom: 203, strony: 110884), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jinorgbio.2019.110884 - link to the publication
  22. Thermographic evaluation of experimental pleurisy induced by carrageenan and modified by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    Authors:
    Piotr Kuropka, Maciej Dobrzyński, Małgorzata Tarnowska, Robert Dymarek, Anna Leśków, Rafał J. Wiglusz
    Academic press:
    Acta of Bioengineering and Biomechanics (rok: 2019, tom: 21, strony: 23-29), Wydawca: Politechnika Wrocławska
    Status:
    Published
    DOI:
    10.5277/ABB-01330-2019-04 - link to the publication
  23. False" cytotoxicity of ions-adsorbing hydroxyapatite – corrected method of cytotoxicity evaluation for ceramics of high specific surface area
    Authors:
    Klimek Katarzyna, Belcarz Anna, Pazik Robert, Sobierajska Paulina, Han Tomasz, Wiglusz Rafal J., Ginalska Grazyna
    Academic press:
    Materials Science & Engineering C (rok: 2016, tom: 65, strony: 70-79), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2016.03.105 - link to the publication
  24. The Protective Effect of α-Tocopherol on the Content of Selected Elements in the Calvaria for Exposed Hens to TCDD in the Early Embryonic Period
    Authors:
    Maciej Dobrzynski, Piotr Kuropka, Malgorzata Tarnowska, Marzena Styczynska, Krzysztof Dudek, Anna Leskow, Sara Targonska, Rafal J. Wiglusz
    Academic press:
    Biological Trace Element Research (rok: 2019, tom: 190, strony: 517-525), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12011-018-1580-y - link to the publication
  25. Venous insufficiency: Differences in the content of trace elements. A preliminary report
    Authors:
    Agnieszka Rusak, Ewa Karuga-Kuźniewska, Benita Wiatrak, Maria Szymonowicz, Mateusz Stolarski, Małgorzata Radwan-Oczko, Rafał J. Wiglusz, Paweł Pohl, Zbigniew Rybak
    Academic press:
    Advances in Clinical and Experimental Medicine (rok: 2018, tom: 27(5), strony: 695-701), Wydawca: Wroclaw Medical University
    Status:
    Published
    DOI:
    10.17219/acem/68902 - link to the publication
  1. BADANIA NANOKOMPOZYTÓW HYDROKSYAPATYTOWYCH WOBEC BAKTERII BEZTLENOWYCH
    Authors:
    Anna Kędziora, Agata Bernat, Rafał J. Wiglusz
    Book:
    Wiadomości chemiczne (rok: 2018, tom: 72, 7-8, strony: 417-447), Wydawca: Polskie Towarzystwo Chemiczne
    Status:
    Published
  2. Nanotechnologia w zastosowaniach biomedycznych
    Authors:
    K. Zawisza, P. Sobierajska, R.J. Wiglusz
    Book:
    Jakość życia - środowiskowe aspekty życia (rok: 2019, tom: -, strony: 71-84), Wydawca: Wydawnictwo Uniwersytetu Ekonomicznego we Wrocławiu
    Status:
    Published

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