Projects funded by the NCN
Studies on the effect of polycation structure on the effectiveness of interactions with nucleic acids in the context of their use in transfections
2012/05/N/ST5/00809
Keywords:
poly(allylamine hydrochloride) polyplexes non-viral vectors transfection
Descriptors:
- ST5_21:
- ST4_13: Solid-state chemistry, surface physicochemistry
- NZ1_1: Molecular biology
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Uniwersytet Jagielloński, Wydział Chemii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 3 - announced on 2012-03-15
Amount awarded: 75 000 PLN
Project start date (Y-m-d): 2013-03-13
Project end date (Y-m-d): 2014-09-12
Project duration:: 18 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Stacja robocza typu laptop.
- Termocykler (20 000 PLN)
- Czytnik mikroplytek.
Information in the final report
- Publication in academic press/journals (2)
- Book publications / chapters in book publications (1)
- Gene delivery efficiency and intracellular trafficking of novel poly(allylamine) derivativesAuthors:Magdalena Wytrwal; Chloe Leduc; Michal Sarna; Cristine Goncalves; Mariusz Kepczynski; Patrick Midoux; Maria Nowakowska; Chantal PichonAcademic press:International Journal of Pharmaceutics (rok: 2015, tom: 478, strony: 372-382), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.ijpharm.2014.11.053 - link to the publication
- Synthesis of strong polycations with improved biological propertiesAuthors:Magdalena Wytrwal, Paulina Koczurkiewicz, Kinga Wójcik, Marta Michalik, Bartłomiej Kozik, Marek Żylewski, Maria Nowakowska, Mariusz KepczynskiAcademic press:Journal of Biomedical Materials Research Part A (rok: 2014, tom: 102, strony: 721-731), Wydawca: WileyStatus:PublishedDOI:10.1002/jbm.a.34744 - link to the publication
- Polyallylamine Derivatives: Novel NonToxic Transfection Agents.Authors:Magdalena Wytrwal, Chantal PichonBook:Non-Viral Gene Delivery Vectors (rok: 2016, tom: 1445, strony: 159-174), Wydawca: Springer New YorkStatus:Published