Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Combination therapy with naphthoquinones and paclitaxel in the pharmacological induction of cell death in breast cancer cells

2011/03/B/NZ7/06144

Keywords:

combination therapy naphthoquinones plant tissue culture paclitaxel breast cancer

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

UNIWERSYTET GDAŃSKI

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Kawiak 

Number of co-investigators in the project: 3

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 288 200 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2015-08-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Aparat do elktroforezy poliakryloamidowej oraz elektrotransferu (10 000 PLN)
  2. Zestaw komputerowy stacjonarny z monitorem Asus 19''LCD.

Information in the final report

  • Publication in academic press/journals (4)
  1. 7-methyljuglone suppresses NF-kB signaling through IKKa inhibition in breast cancer cells.
    Authors:
    Kawiak Anna, Lojkowska E
    Academic press:
    Acta Biochimica Polonica (rok: 2015, tom: 62 (Suppl 1), strony: 35), Wydawca: Polish Biochemical Society
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Ramentaceone from Drosera aliciae inhibits NF-κB signaling and induces apoptosis in breast cancer cells.
    Authors:
    Kawiak Anna, Ewa Lojkowska
    Academic press:
    Anti-Cancer Drugs (rok: 2015, tom: 26 (Suppl 1), strony: e14), Wydawca: Wolters Kluwer
    Status:
    Published
    DOI:
    10.1097/CAD.0000000000000280 - link to the publication
  3. 3-Chloroplumbagin inhibits MAPK/ERK signaling and induces apoptotic cell death in breast cancer cells.
    Authors:
    Domachowska Anna, Fajerabend Monika, Lojkowksa Ewa, Kawiak Anna
    Academic press:
    Anti-Cancer Drugs (rok: 2015, tom: 26 (Suppl 1), strony: e37), Wydawca: Wolters Kluwer
    Status:
    Published
    DOI:
    10.1097/CAD.0000000000000280 - link to the publication
  4. Ramentaceone, a Naphthoquinone Derived from Drosera sp., Induces Apoptosis by Suppressing PI3K/Akt Signaling in Breast Cancer Cells
    Authors:
    Kawiak A, Lojkowska E
    Academic press:
    PLOS ONE (rok: 2016, tom: 11 (2), strony: e0147718), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0147718 - link to the publication

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