Projects funded by the NCN
The role of transcription factors Stat1 and Stat3 in transcriptional regulation of uba7 and jmjd3, crucial mediators of inflammation
2011/03/N/NZ1/03143
Keywords:
Stat1 Stat3 Uba7 transcription regulation ubiquitination mikroglej stan zapalny
Descriptors:
- NZ1_1: Molecular biology
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Instytut Biologii Doświadczalnej im. M. Nenckiego PAN
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 2 - announced on 2011-09-15
Amount awarded: 161 000 PLN
Project start date (Y-m-d): 2012-08-27
Project end date (Y-m-d): 2014-02-26
Project duration:: 18 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- mikrowirówka miniSpin (Ependorf) (4 534 PLN)
Information in the final report
- Publication in academic press/journals (2)
- ISG'ylation increases stability of numerous proteins including Stat1, which prevents premature termination of immune response in LPS-stimulated microgliaAuthors:Piotr Przanowski, Stefan Loska, Dominik Cysewski, Michal Dabrowski, Bozena KaminskaAcademic press:Neurochemistry International (rok: 2017, tom: -, strony: [Epub ahead of print]), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.neuint.2017.07.013 - link to the publication
- The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia.Authors:Przanowski P, Dabrowski M, Ellert-Miklaszewska A, Kloss M, Mieczkowski J, Kaza B, Ronowicz A, Hu F, Piotrowski A, Kettenmann H, Komorowski J, Kaminska B.Academic press:Journal of Molecular Medicine (rok: 2014, tom: 92, Issue 3, strony: 239-254), Wydawca: SPRINGERStatus:PublishedDOI:10.1007/s00109-013-1090-5 - link to the publication