Reconstitution of hematopoietic stem cell niche after allogeneic stem cell transplantation

2011/03/B/NZ6/04917

Keywords

Descriptors

  • NZ3_8: Komórki macierzyste
  • NZ6_2: Immunologia kliniczna

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Sebastian Giebel

Number of co-investigators in the project: 10

Call

OPUS 2 – announced on 2011-09-15

Amount awarded
400 000 PLN
Project start date
2012-09-06
Project end date
2015-09-05
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (1)

  1. Immunological properties of bone marrow microenvironment 1 year after allogeneic hematopoietic stem cell transplantation.

    Authors:
    Agnieszka Ciomber, Iwona Mitrus, Wojciech Fidyk, Andrzej Smagur, Agata Chwieduk, Magdalena Głowala-Kosińska, Tomasz Czerw, Małgorzata Sobczyk-Kruszelnicka, Włodzimierz Mendrek, Maria Saduś-Wojciechowska, Jacek. Najda, Jerzy Holowiecki, Sebastian Giebel
    Status:
    Accepted for publication

Articles in post-conference publications (5)

  1. The impact of proinflammatory and immunosuppressive cytokines on the expression of CD47 and CD274 on the HSCs

    Authors:
    A. Ciomber, W. Fidyk, I. Mitrus, M. Głowala-Kosińska, A. Smagur, S. Giebel
    Conference:
    XV Zjazd Towarzystwa Immunologii Doświadczalnej i Klinicznej (year: 2014, pages: 6), Publisher: Central European Journal of Immunology
    Date:
    conference 26-28 czerwca
    Status:
    Published
  2. Increased expression of CD47 and CD274 immunosuppressive proteins on HSCs after allogeneic HSCs transplantation.

    Authors:
    A. Ciomber, I. Mitrus, W. Fidyk, A. Smagur, S. Giebel
    Conference:
    48 Zjazd PTBioch (year: 2013, pages: 78), Publisher: Acta Biochimica Polonica, supplement 1/2013
    Date:
    conference 2-5 września 2013
    Status:
    Published
    DOI:
    link to the publication
  3. Immunosuppressive properties of bone marrow microenvironment after allo-HSC transplanation

    Authors:
    Smagur A., Ciomber A., Mitrus I, Głowala-Kosińska M., Fidyk W., Giebel S.
    Conference:
    The Immune System and the Microenvironment - Implication for Cancer Therapy (year: 2015, pages: 33), Publisher: Institute for Cancer Research, The Radium Hospital, Oslo, Norway
    Date:
    conference 24-25 sierpnia
    Status:
    Published
  4. CD274 expression on HSCs is increased after chemo- and radiotherapy

    Authors:
    Ciomber A, Mitrus I, Fidyk W, Smagur A, Głowala-Kosińska M, Giebel S
    Conference:
    Monocytes, dendritic cells and macrophages – basic research and pathophysiological aspects - 29th Annual Conference of the EMDS 2015 (year: 2015, pages: 47-48), Publisher: European Macrophage & Dendritic Cell Society
    Date:
    conference 11-13 września
    Status:
    Published
  5. Expression of immunosuppressive protein CD47 in hematopoietic stem cells is lower in blood than in bone marrow

    Authors:
    I. Mitrus, A. Ciomber, W. Fidyk, A. Smagur, M Głowala-Kosińska, S. Giebel
    Conference:
    Stem Cells in Cancer and Regenerative Medicine (year: 2014, pages: 151), Publisher: EMBO
    Date:
    conference 8-12 października
    Status:
    Published

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