Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Partial agonists alpha1A/D-adrenoceptors as potential compounds that improve urodynamic parameters in benign prostatic hyperplasia

2011/03/B/NZ7/00724

Keywords:

partial agonist of alpha1-adrenoceptor benign prostatic hyperplasia

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ5_7: Human disease treatment

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jacek Sapa 

Number of co-investigators in the project: 17

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 747 160 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2016-08-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputer do obsługi aparatu do pomiaru ciśnienia metodą krwawą u małych zwierząt.
  2. Notebook + oprogramowanie (10 000 PLN)
  3. Wytrząsarka do płytek (5 000 PLN)
  4. Router.
  5. Aparat EKG (10 000 PLN)
  6. Wyposażenie syntetyzera.
  7. Aparat do izolowanych narządów (100 000 PLN)
  8. Aparat do pomiaru ciśnienia metodą krwawą u małych zwierząt (50 000 PLN)
  9. Homogenizator (10 000 PLN)
  10. Kardiomonitor weterynaryjny z mankietem dla małych zwierząt.
  11. Mieszadło.
  12. Pompa próżniowa.
  13. Programy komputerowe (Microsoft Office for Windows and Microsoft Office for Mac).
  14. Notebook do obsługi aparatu do izolowanych narządów.
  15. Syntetyzer (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  1. Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines as α1-adrenergic receptor antagonist with uro-selective activity.
    Authors:
    Rak A, Canale V, Marciniec K, Żmudzki P, Kotańska M, Knutelska J, Siwek A, Stachowicz G, Bednarski M, Nowiński L, Zygmunt M, Zajdel P, Sapa J.
    Academic press:
    Bioorg Med Chem. (rok: 2016, tom: 10, strony: 45301), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bmc.2016.09.017 - link to the publication