Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Analysis of molecular background of clear cell renal cell carcinoma and role of MCPIP1 in tomorigenesis

2011/03/B/NZ1/00023

Keywords:

polymorphism genetic association gene expression MCPIP NFkappaB and MAP kinase activity

Descriptors:

  • NZ1_1: Molecular biology
  • NZ2_1: Molecular genetics
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jolanta Jura 

Number of co-investigators in the project: 13

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 763 000 PLN

Project start date (Y-m-d): 2012-08-02

Project end date (Y-m-d): 2016-02-01

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. System do dokumentacji żeli (100 000 PLN)
  2. mikroskop diagnostyczny.

Information in the final report

  • Publication in academic press/journals (4)
  1. MCPIP1 contributes to the toxicity of proteasome inhibitor MG-132 in HeLa cells by the inhibition of NF-κB.
    Authors:
    Skalniak L, Dziendziel M, Jura J.
    Academic press:
    Mol. Cell Biochem (rok: 2014, tom: 375, strony: 253-263), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11010-014-2134-z - link to the publication
  2. Variants of SCARB1 and VDR Involved in Complex Genetic Interactions May Be Implicated in the Genetic Susceptibility to Clear Cell Renal Cell Carcinoma.
    Authors:
    Pośpiech E, Ligęza J, Wilk W, Gołas A, Jaszczyński J, Stelmach A, Ryś J, Blecharczyk A, Wojas-Pelc A, Jura J, Branicki W.
    Academic press:
    Biomed Res Int. (rok: 2015, tom: 860405, strony: 45302), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2015/860405 - link to the publication
  3. MCPIP1 contributes to clear-cell renal cell carcinomas development
    Authors:
    Janusz Ligeza, Paulina Marona, Natalia Gach, Barbara Lipert, Katarzyna Miekus, Waclaw Wilk, Janusz Jaszczynski, Andrzej Stelmach, Agnieszka Loboda, Jozef Dulak, Wojciech Branicki, Janusz Rys, Jolanta Jura
    Academic press:
    Angiogenesis (rok: 2016, tom: nt, strony: nt), Wydawca: Springer
    Status:
    Submitted
    DOI:
    brak - link to the publication
  4. Modulatory Effects of Curcumin and Tyrphostins (AG494 and AG1478) on Growth Regulation and Viability of LN229 Human Brain Cancer Cells.
    Authors:
    Bojko A, Cierniak A, Adamczyk A, Ligeza J.
    Academic press:
    Nutr Cancer (rok: 2015, tom: 67, strony: 1170-1182), Wydawca: Taylor and Francis
    Status:
    Published
    DOI:
    10.1080/01635581.2015.1073764 - link to the publication

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