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The role of the lectin pathway of complement activation in the development of complications after pediatric cardiac surgery with the use of cardiopulmonary bypass

2011/03/B/NZ6/00052

Keywords

Descriptors

  • NZ6_1: Odporność swoista i nieswoista

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Instytut Centrum Zdrowia Matki Polki

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Izabela Pągowska-Klimek

Number of co-investigators in the project: 7

Call

OPUS 2 – announced on 2011-09-15

Amount awarded
256 000 PLN
Project start date
2012-09-04
Project end date
2016-01-03
Project duration
40 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. zamrażarka niskotemperaturowa. Cost: 28 000 PLN

Information in the final report

Publication in academic press/journals (4)

  1. Primary Ficolin-3 deficiency - Is it associated with increased susceptibility to infections?

    Authors:
    Michalski M, Świerzko AS, Pągowska-Klimek I, Niemir ZI, Mazerant K, Domżalska-Popadiuk I, Moll M, Cedzyński M
    Academic press:
    Immunobiology (year: 2015, volume: 46041, pages: S0171-2985(15)00005-4.), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.imbio.2015.01.003 – link to the publication

  2. Mannan binding lectin in cardiovascular disease

    Authors:
    Pagowska-Klimek Izabela, Maciej Cedzyński
    Academic press:
    Biomed Research International (year: 2014, volume: 2014:616817, pages: 46035), Publisher: Hidawi
    Status:
    Published
    DOI:
    10.1155/2014/616817 – link to the publication

  3. Mannose-binding lectin (MBL) insufficiency protects against the development of systemic inflammatory response after pediatric cardiac surgery.

    Authors:
    Pągowska-Klimek I, Świerzko AS, Michalski M, Moll M, Szala-Poździej A, Sokołowska A, Krajewski WR, Cedzyński M
    Academic press:
    Immunobiology (year: 2016, volume: 221 (2), pages: 175-81), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.imbio.2015.09.010 – link to the publication

  4. Activation of the lectin pathway of complement by cardiopulmonary bypass contributes to the development of systemic inflammatory response syndrome after pediatric cardiac surgery.

    Authors:
    Pągowska-Klimek I, Świerzko AS, Michalski M, Głowacka E, Szala-Poździej A, Sokołowska A, Moll M, Krajewski WR, Romak J, Cedzyński M
    Status:
    Accepted for publication

Articles in post-conference publications (4)

  1. Mannose-binding lectin (MBL) insufficiency protects against the development of systemic inflammatory response after pediatric cardiac surgery.

    Authors:
    Świerzko AS
    Conference:
    Innate Immunity (year: 2015, pages: 52), Publisher: J Clin Cell Immunol 2015
    Date:
    conference 20-21 lipca 2015
    Status:
    Published

  2. Mannose-binding lectin (MBL) insufficiency protects against the development of systemic inflammatory response after pediatric cardiac surgery.

    Authors:
    Pągowska-Klimek I, Świerzko AS, Michalski M, Moll M, Szala-Poździej A, Sokołowska A, Krajewski WR, Cedzyński M
    Conference:
    8th Conference on Complement Therapeutics (year: 2015, pages: 86), Publisher: Aegean Conferences Series
    Date:
    conference 1-6.09.2015
    Status:
    Published

  3. Pre-operative ficolin-3 concentrations in relation to copmlications following pediatric cardiac surgery

    Authors:
    Michalsi M, Świerzko A, Cedzyński M., Krajeewski W., Moll M., Pągowska-Klimek I.
    Conference:
    8 th Conference on Complement Therapeutics (year: 2015, pages: 84), Publisher: Aegean Conferences Series
    Date:
    conference 1-6.09.2015
    Status:
    Published

  4. complement lectin pathway activation by cardiopulmonary bypass contributes to thedevelopment of systemic inflammatory response syndrome after pediatriccardiac surgery

    Authors:
    Pągowska-Klimek I, Świerzko AS, Michalski M, Moll M, Szala-Poździej A, Sokołowska A, Krajewski WR,Cedzyński M
    Conference:
    8th conference on Complement Therapeutics (year: 2015, pages: 85), Publisher: Aegean Conferences Series
    Date:
    conference 1-6.09.2015
    Status:
    Published

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