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Information on the principal investigator and host institution

Information of the project and the call

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Profiling of neuthrophil handprints in granulomatosis with polyangiitis (Wegener's)

2011/03/N/NZ6/01578

Keywords:

neutrophil gene expression cANCA,granulomatosis with polyangiitis (Wegener's) platelet activation endothelilal cell activation

Descriptors:

  • NZ1_1: Molecular biology
  • NZ6_2: Clinical immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marcin Surmiak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 352 105 PLN

Project start date (Y-m-d): 2012-10-10

Project end date (Y-m-d): 2015-06-09

Project duration:: 32 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (4)
  1. Neutrophil-related and serum biomarkers in granulomatosis with polyangiitis support extracellular traps mechanism of the disease
    Authors:
    Marcin Surmiak,Magdalena Hubalewska-Mazgaj, Katarzyna Wawrzycka-Adamczyk, Wojciech Szczeklik, Jacek Musiał, Tomasz Brzozowski,Marek Sanak
    Academic press:
    Clinical and Experimental Rheumatology (rok: 2016, tom: 34, strony: 98-104), Wydawca: Clinical and Experimental Rheumatology
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Apoptosis genes expression in neutrophils of patients with granulomatosis with polyangiitis
    Authors:
    Marcin Surmiak, Magdalena Hubalewska-Mazgaj, Katarzyna Wawrzycka-Adamczyk, Jacek Musiał, Marek Sanak
    Academic press:
    Cellular & Molecular Immunology (rok: 2017, ), Wydawca: Springer Nature
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. Circulating mitochondrial DNA in serum of patients with granulomatosis with polyangiitis
    Authors:
    Surmiak Marcin Piotr, Hubalewska-Mazgaj Magdalena, Wawrzycka-Adamczyk Katarzyna, Szczeklik Wojciech, Musiał Jacek, Sanak Marek
    Academic press:
    Clinical & Experimental Immunology (rok: 2015, tom: 181, strony: 150-155), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.111/cei.12628 - link to the publication
  4. Proinflammatory genes expression in granulocytes activated by native proteinase-binding fragments of anti-PR3 IgG
    Authors:
    Marcin Surmiak, Marcin Kaczor, Marek Sanak
    Academic press:
    Journal of Physiology and Pharmacology (rok: 2015, tom: 4, strony: 609-615), Wydawca: Polish Physiological Society
    Status:
    Published
    DOI:
    brak - link to the publication
  5. Neutrophil MiRNA-128-3p is Decreased During Active Phase of Granulomatosis with Polyangiitis
    Authors:
    Marcin Surmiak, Magdalena Hubalewska-Mazgaj, Katarzyna Wawrzycka-Adamczyk, Jacek Musial and Marek Sanak
    Academic press:
    Current Genomics (rok: 2015, tom: 16, strony: 359-365), Wydawca: Bentham Science
    Status:
    Published
    DOI:
    10.2174/1389202916666150707160434 - link to the publication
  1. Expression Profile of Apoptosis-Related Genes in Neutrophils from Granulomatosis with Polyangiitis Patients
    Authors:
    Marcin Surmiak, Magdalena Hubalewska-Mazgaj, Katarzyna Wawrzycka, Marek Sanak
    Conference:
    17th International Vasculitis & ANCA Workshop (rok: 2015, ), Wydawca: Karger
    Data:
    konferencja 19-22 Kwietnia
    Status:
    Published
  2. Platelet-neutrophil aggregates are elevated in active stage of granulomatosis with polyangiitis and correlated with the disease activity score
    Authors:
    Marcin Surmiak, Magdalena Hubalewska-Mazgaj, Katarzyna Wawrzycka, Wojciech Szczeklik, Marek Sanak
    Conference:
    9th International Congress on Autoimmunity (rok: 2014, ), Wydawca: Kenes
    Data:
    konferencja 26-30 Marzec
    Status:
    Published
  3. Granulomatosis with polyangiitis is characterized by decreased spontaneous apoptosis of circulationg neutrophils
    Authors:
    Magdalena Hubalewska-Mazgaj, Marcin Surmiak, Katarzyna Wawrzycka, Wojciech Szczeklik, Marek Sanak
    Conference:
    9th International Congress on Autoimmunity (rok: 2014, ), Wydawca: Kenes
    Data:
    konferencja 26-30 Marzec
    Status:
    Published
  4. Serum Level of Cell Free Circulating Mitochondrial DNA in patients with Granulomatosis with Polyangiitis
    Authors:
    Marcin Surmiak, Magdalena Hubalewska-Mazgaj, Katarzyna Wawrzycka-Adamczyk, Marek Sanak
    Conference:
    17th International Vasculitis & ANCA Workshop (rok: 2015, ), Wydawca: Karger
    Data:
    konferencja 19-22 Kwietnia
    Status:
    Published

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