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Antiphospholipid syndrome - an autoimmune disease of the cardiovascular system. Pathogenetic role of the (auto)immune inflammation and activation of haemostasis

2011/03/B/NZ6/01608

Keywords

Descriptors

  • NZ6_2: Immunologia kliniczna

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Jacek Musiał

Number of co-investigators in the project: 10

Call

OPUS 2 – announced on 2011-09-15

Amount awarded
807 400 PLN
Project start date
2012-08-22
Project end date
2015-08-21
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Filtry do czytnika fluorescencyjnego. Cost: 4 999 PLN
  2. Mikropłuczka (Biokom, Wielka Brytania). Cost: 60 000 PLN
  3. Mikrowirówka (Szybkoobrotowa). Cost: 35 000 PLN
  4. Pipeta.
  5. Zamrażarka.

Information in the final report

Publication in academic press/journals (4)

  1. Signs of impaired immunoregulation and enhanced effector T-cell responses in the primary antiphopsholipid syndrome

    Authors:
    B. Jakiela, T. Iwaniec, H. Plutecka, M. Celinska-Lowenhoff, S. Dziedzina, J. Musial.
    Academic press:
    Lupus (year: 2016, volume: 25, pages: 389-98), Publisher: SAGE Publications
    Status:
    Published

  2. Risk factors for arterial thrombosis in antiphospholipid syndrome.

    Authors:
    A. Matyja-Bednarczyk, J. Swadźba, T. Iwaniec, M. Sanak, S. Dziedzina, A. Ćmiel, J. Musiał.
    Academic press:
    Thromb. Res. 2014; 133: 173-176. (year: 2014, volume: 133, pages: 173-176), Publisher: PERGAMON-ELSEVIER SCIENCE LTD
    Status:
    Published

  3. Altered fibrin clot structure/function in patients with antiphospholipid syndrome: association with thrombotic manifestation.

    Authors:
    Celińska-Lowenhoff M, Iwaniec T, Padjas A, Musiał J, Undas A.
    Academic press:
    Thromb Haemost. (year: 2014, volume: 112, pages: 287-296), Publisher: Schattauer
    Status:
    Published
    DOI:
    10.1160/TH13-11-0980 – link to the publication

  4. Clinical utility of automated chemiluminescent antiphospholipid antibody assay.

    Authors:
    T. Iwaniec, MP Kaczor, M. Celińska-Löwenhoff, S. Polański, J. Musiał.
    Academic press:
    Thromb Res (year: 2015, volume: vol 136, pages: 501-508), Publisher: PERGAMON-ELSEVIER SCIENCE LTD
    Status:
    Published
    DOI:
    link to the publication

Articles in post-conference publications (6)

  1. Myocardial ischaemia and coronary atherosclerosis in patients with antiphospholipid syndrome

    Authors:
    Padjas A, Plazak W, Celińska-Lowenhoff M, Iwaniec T, Swadzba J, Luberda T, Podolec P, Musial J
    Conference:
    XXIV ISTH Congress, Amsterdam 2013 (year: 2013, pages: PB 2. 62-1), Publisher: Wiley-Blacwell
    Date:
    conference 29.06-04.07
    Status:
    Published
    DOI:
    link to the publication

  2. Contribution of immunoregulatory cytokines in the pathogenesis of primary antiphospholipid syndrome

    Authors:
    Iwaniec T, Jakiela B, Celinska-Lowenhoff M, Swadzba J, Padjas A, Musial J
    Conference:
    XXIV ISTH Congress, Amsterdam (year: 2013, pages: PB 3 62-3), Publisher: Wiley-Blackwell
    Date:
    conference 29.06-04.07.
    Status:
    Published
    DOI:
    link to the publication

  3. Fibrin clot properties in patients with antiphospholipid syndrome

    Authors:
    Celinska-Lowenhoff M, Iwaniec T, Padjas A, Musial j, Undas A
    Conference:
    XXIV ISTH Congress, Amsterdam (year: 2013, pages: AS 08-3), Publisher: Wiley-Blackwell
    Date:
    conference 29.06.-04.07
    Status:
    Published
    DOI:
    link to the publication

  4. Analytical and clinical performance of a new automated chemiluminescent assay (CIA)

    Authors:
    Iwaniec T, Kaczor MP, Celinska-Lowenhoff M, Polanski S and Musiał J
    Conference:
    XXV Congress of the International Society on Thrombosis and Haemostasis (year: 2015, pages: PO048), Publisher: Wiley-Blackwell
    Date:
    conference 20.06–25.06
    Status:
    Published
    DOI:
    link to the publication

  5. The association of 3 STAT4 single nucleotide polymorphisms and antiphospholipid syndrome

    Authors:
    Celinska-Lowenhoff MM, Iwaniec T, Dziedzina S, Kaczor M, Sanak M and Musial J.
    Conference:
    XXV Congress of the International Society on Thrombosis and Haemostasis, (year: 2015, pages: PO070), Publisher: Wiley-Blackwell
    Date:
    conference 20.06–25.06
    Status:
    Published
    DOI:
    link to the publication

  6. Evaluation of Β 2-glycoprotein I levels in patients with antiphospholipid syndrome.

    Authors:
    Iwaniec T, Celinska-Lowenhoff M, Kaczor M and Musiał J.
    Conference:
    XXV Congress of the International Society on Thrombosis and Haemostasis, (year: 2015, pages: PO069), Publisher: Wiley-Blackwell
    Date:
    conference 20.06–25.06
    Status:
    Published
    DOI:
    link to the publication

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