Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Antiphospholipid syndrome - an autoimmune disease of the cardiovascular system. Pathogenetic role of the (auto)immune inflammation and activation of haemostasis

2011/03/B/NZ6/01608

Keywords:

antiphospholipid syndrome cardiovascular system inflammation haemostasis

Descriptors:

  • NZ6_2: Clinical immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jacek Musiał 

Number of co-investigators in the project: 10

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 807 400 PLN

Project start date (Y-m-d): 2012-08-22

Project end date (Y-m-d): 2015-08-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Mikropłuczka (Biokom, Wielka Brytania) (60 000 PLN)
  2. Pipeta.
  3. Filtry do czytnika fluorescencyjnego (4 999 PLN)
  4. Mikrowirówka (Szybkoobrotowa) (35 000 PLN)
  5. Zamrażarka.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (6)
  1. Signs of impaired immunoregulation and enhanced effector T-cell responses in the primary antiphopsholipid syndrome
    Authors:
    B. Jakiela, T. Iwaniec, H. Plutecka, M. Celinska-Lowenhoff, S. Dziedzina, J. Musial.
    Academic press:
    Lupus (rok: 2016, tom: 25, strony: 389-98), Wydawca: SAGE Publications
    Status:
    Published
  2. Risk factors for arterial thrombosis in antiphospholipid syndrome.
    Authors:
    A. Matyja-Bednarczyk, J. Swadźba, T. Iwaniec, M. Sanak, S. Dziedzina, A. Ćmiel, J. Musiał.
    Academic press:
    Thromb. Res. 2014; 133: 173-176. (rok: 2014, tom: 133, strony: 173-176), Wydawca: PERGAMON-ELSEVIER SCIENCE LTD
    Status:
    Published
  3. Altered fibrin clot structure/function in patients with antiphospholipid syndrome: association with thrombotic manifestation.
    Authors:
    Celińska-Lowenhoff M, Iwaniec T, Padjas A, Musiał J, Undas A.
    Academic press:
    Thromb Haemost. (rok: 2014, tom: 112, strony: 287-296), Wydawca: Schattauer
    Status:
    Published
    DOI:
    10.1160/TH13-11-0980 - link to the publication
  4. Clinical utility of automated chemiluminescent antiphospholipid antibody assay.
    Authors:
    T. Iwaniec, MP Kaczor, M. Celińska-Löwenhoff, S. Polański, J. Musiał.
    Academic press:
    Thromb Res (rok: 2015, tom: vol 136, strony: 501-508), Wydawca: PERGAMON-ELSEVIER SCIENCE LTD
    Status:
    Published
  1. The association of 3 STAT4 single nucleotide polymorphisms and antiphospholipid syndrome
    Authors:
    Celinska-Lowenhoff MM, Iwaniec T, Dziedzina S, Kaczor M, Sanak M and Musial J.
    Conference:
    XXV Congress of the International Society on Thrombosis and Haemostasis, (rok: 2015, ), Wydawca: Wiley-Blackwell
    Data:
    konferencja 20.06–25.06
    Status:
    Published
  2. Contribution of immunoregulatory cytokines in the pathogenesis of primary antiphospholipid syndrome
    Authors:
    Iwaniec T, Jakiela B, Celinska-Lowenhoff M, Swadzba J, Padjas A, Musial J
    Conference:
    XXIV ISTH Congress, Amsterdam (rok: 2013, ), Wydawca: Wiley-Blackwell
    Data:
    konferencja 29.06-04.07.
    Status:
    Published
  3. Evaluation of Β 2-glycoprotein I levels in patients with antiphospholipid syndrome.
    Authors:
    Iwaniec T, Celinska-Lowenhoff M, Kaczor M and Musiał J.
    Conference:
    XXV Congress of the International Society on Thrombosis and Haemostasis, (rok: 2015, ), Wydawca: Wiley-Blackwell
    Data:
    konferencja 20.06–25.06
    Status:
    Published
  4. Fibrin clot properties in patients with antiphospholipid syndrome
    Authors:
    Celinska-Lowenhoff M, Iwaniec T, Padjas A, Musial j, Undas A
    Conference:
    XXIV ISTH Congress, Amsterdam (rok: 2013, ), Wydawca: Wiley-Blackwell
    Data:
    konferencja 29.06.-04.07
    Status:
    Published
  5. Myocardial ischaemia and coronary atherosclerosis in patients with antiphospholipid syndrome
    Authors:
    Padjas A, Plazak W, Celińska-Lowenhoff M, Iwaniec T, Swadzba J, Luberda T, Podolec P, Musial J
    Conference:
    XXIV ISTH Congress, Amsterdam 2013 (rok: 2013, ), Wydawca: Wiley-Blacwell
    Data:
    konferencja 29.06-04.07
    Status:
    Published
  6. Analytical and clinical performance of a new automated chemiluminescent assay (CIA)
    Authors:
    Iwaniec T, Kaczor MP, Celinska-Lowenhoff M, Polanski S and Musiał J
    Conference:
    XXV Congress of the International Society on Thrombosis and Haemostasis (rok: 2015, ), Wydawca: Wiley-Blackwell
    Data:
    konferencja 20.06–25.06
    Status:
    Published